Iron oxide nanoparticles (IONPs) have been extensively used during the last two decades,
either as effective bio-imaging contrast agents or as carriers of biomolecules such as drugs …

The idea of employing natural cell membranes as a coating medium for nanoparticles (NPs)
endows man-made vectors with natural capabilities and benefits. In addition to retaining the …

High-grade glioma is one of the most aggressive types of cancer with a low survival rate
ranging from 12 to 15 months after the first diagnosis. Though being the most common …

Chemotherapy for brain glioma has been of limited value due to the inability of transport of
drug across the blood-brain barrier (BBB) and poor penetration of drug into the tumor. For …

In this review we will describe eight commonly used rat brain tumor models and their
application for the development of novel therapeutic and diagnostic modalities. The C6, 9L …

Background: Glioblastoma multiforme is the most aggressive brain tumor with poor
prognosis and an average survival of 1-2 years. Animal models that simulate the features of …

Drug delivery systems (DDS) have recently emerged as a promising approach for the
unique advantages of drug protection and targeted delivery. However, the access of …

The ability of nanoparticles and macromolecules to passively accumulate in solid tumors
and enhance therapeutic effects in comparison with conventional anticancer agents has …

Drug delivery systems, particularly nanomaterial-based drug delivery systems, possess a
tremendous amount of potential to improve the diagnostic and therapeutic effects of drugs …

The prognosis of patients with malignant glioma remains extremely poor, despite surgery
and improvements in radio-and chemo-therapies. Nanotechnologies represent great …