Macrophage scavenger receptors: Tumor support and tumor inhibition
Tumor-associated macrophages (TAMs) are a heterogeneous population of myeloid cells
that constitute up to 50% of the cell mass of human tumors. TAMs interact with the …
that constitute up to 50% of the cell mass of human tumors. TAMs interact with the …
Immune microenvironment and response in prostate cancer using large population cohorts
X Ren, X Chen, X Zhang, S Jiang, T Zhang… - Frontiers in …, 2021 - frontiersin.org
Immune microenvironment of prostate cancer (PCa) is implicated in disease progression.
However, previous studies have not fully explored PCa immune microenvironment. This …
However, previous studies have not fully explored PCa immune microenvironment. This …
Neurodevelopmental disorders and cancer networks share pathways, but differ in mechanisms, signaling strength, and outcome
Epidemiological studies suggest that individuals with neurodevelopmental disorders (NDDs)
are more prone to develop certain types of cancer. Notably, however, the case statistics can …
are more prone to develop certain types of cancer. Notably, however, the case statistics can …
Breast Tumor Metastasis and Its Microenvironment: It Takes Both Seed and Soil to Grow a Tumor and Target It for Treatment
Simple Summary Metastasis is one of the biggest challenges in treating breast cancer.
Breast tumors grow in different areas such as the brain, lungs and bone and have distinct …
Breast tumors grow in different areas such as the brain, lungs and bone and have distinct …
[HTML][HTML] Unveiling pathogenic mutations in BRCA1 and BRCA2 genes across head and neck squamous cell carcinoma patients via next generation sequencing
X Wei, Z Tian, F Zhao, A Sun, S Zhao… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Abstract Head and Neck Squamous Cell Carcinoma (HNSC) presents a formidable
challenge in the field of oncology due to its aggressive nature and the limited therapeutic …
challenge in the field of oncology due to its aggressive nature and the limited therapeutic …
Comprehensive genomic profiling reveals prognostic signatures and insights into the molecular landscape of colorectal cancer
J Yang, S Zhao, J Su, S Liu, Z Wu, W Ma… - Frontiers in …, 2023 - frontiersin.org
Background Colorectal cancer (CRC) is a prevalent malignancy with diverse molecular
characteristics. The NGS-based approach enhances our comprehension of genomic …
characteristics. The NGS-based approach enhances our comprehension of genomic …
Kinase Insert Domain Receptor Q472H Pathogenic Germline Variant Impacts Melanoma Tumor Growth and Patient Treatment Outcomes
Simple Summary Despite the improvement in melanoma treatment over the last decade,
there is still a need for develo** new treatment strategies that can achieve complete and …
there is still a need for develo** new treatment strategies that can achieve complete and …
Deciphering gene contributions and etiologies of somatic mutational signatures of cancer
X Ji, E Wang, Q Cui - Briefings in Bioinformatics, 2023 - academic.oup.com
Somatic mutational signatures (MSs) identified by genome sequencing play important roles
in exploring the cause and development of cancer. Thus far, many such signatures have …
in exploring the cause and development of cancer. Thus far, many such signatures have …
Predicting cancer risk from germline whole-exome sequencing data using a novel context-based variant aggregation approach
Many studies have shown that the distributions of the genomic, nucleotide, and epigenetic
contexts of somatic variants in tumors are informative of cancer etiology. Recently, a new …
contexts of somatic variants in tumors are informative of cancer etiology. Recently, a new …