The ancillary effects of nanoparticles and their implications for nanomedicine
Nanoparticles are often engineered as a scaffolding system to combine targeting, imaging
and/or therapeutic moieties into a unitary agent. However, mostly overlooked, the …
and/or therapeutic moieties into a unitary agent. However, mostly overlooked, the …
Novel approaches to immunomodulation for solid organ transplantation
I Husain, X Luo - Annual Review of Medicine, 2024 - annualreviews.org
Despite significant advances in the field of transplantation in the past two decades, current
clinically available therapeutic options for immunomodulation remain fairly limited. The …
clinically available therapeutic options for immunomodulation remain fairly limited. The …
Engineering the lymph node environment promotes antigen-specific efficacy in type 1 diabetes and islet transplantation
JM Gammon, ST Carey, V Saxena, HB Eppler… - Nature …, 2023 - nature.com
Antigen-specific tolerance is a key goal of experimental immunotherapies for autoimmune
disease and allograft rejection. This outcome could selectively inhibit detrimental …
disease and allograft rejection. This outcome could selectively inhibit detrimental …
Polymer nanotherapeutics to correct autoimmunity
T Su, X Feng, J Yang, W Xu, T Liu, M Zhang… - Journal of Controlled …, 2022 - Elsevier
The immune system maintains homeostasis and protects the body from pathogens, mutated
cells, and other harmful substances. When immune homeostasis is disrupted, excessive …
cells, and other harmful substances. When immune homeostasis is disrupted, excessive …
Biomaterial strategies for selective immune tolerance: advances and gaps
ST Carey, C Bridgeman, CM Jewell - Advanced Science, 2023 - Wiley Online Library
Autoimmunity and allergies affect a large number of people across the globe. Current
approaches to these diseases target cell types and pathways that drive disease, but these …
approaches to these diseases target cell types and pathways that drive disease, but these …
Cargo-less nanoparticles program innate immune cell responses to toll-like receptor activation
Develo** biomaterials to control the responsiveness of innate immune cells represents a
clinically relevant approach to treat diseases with an underlying inflammatory basis, such as …
clinically relevant approach to treat diseases with an underlying inflammatory basis, such as …
Nanotechnology applications in transplantation medicine
CG Yao, PN Martins - Transplantation, 2020 - journals.lww.com
A recent technological advance that shows promise for applications in health care, including
transplantation medicine, is the implementation of nanoparticles. Nanoparticles can be …
transplantation medicine, is the implementation of nanoparticles. Nanoparticles can be …
Nanoparticle platforms for antigen-specific immune tolerance
Innovative approaches in nanoparticle design have facilitated the creation of new
formulations of nanoparticles that are capable of selectively calibrating the immune …
formulations of nanoparticles that are capable of selectively calibrating the immune …
Engineering immunity using metabolically active polymeric nanoparticles
KV Griffin, MN Saunders, CA Lyssiotis, LD Shea - Trends in Biotechnology, 2024 - cell.com
Immune system functions play crucial roles in both health and disease, and these functions
are regulated by their metabolic programming. The field of immune engineering has …
are regulated by their metabolic programming. The field of immune engineering has …
Nanomedicine and nanoparticle-based delivery systems in plastic and reconstructive surgery
Background Nanotechnology and nanomedicine are rising novel fields in plastic and
reconstructive surgery (PRS). The use of nanomaterials often goes with regenerative …
reconstructive surgery (PRS). The use of nanomaterials often goes with regenerative …