Genetic code expansion and reprogramming enable the site-specific incorporation of
diverse designer amino acids into proteins produced in cells and animals. Recent advances …

The unicellular alga Chlamydomonas reinhardtii is a classical reference organism for
studying photosynthesis, chloroplast biology, cell cycle control, and cilia structure and …

The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic
creates a significant threat to global health. Recent studies suggested the significance of …

By the onset of morphogenesis, Drosophila embryos consist of about 6000 cells that express
distinct gene combinations. Here, we used single-cell sequencing of precisely staged …

Understanding how gene regulatory networks control the progressive restriction of cell fates
is a long-standing challenge. Recent advances in measuring gene expression in single cells …

Fruit flies of the genus Drosophila have been an attractive and effective genetic model
organism since Thomas Hunt Morgan and colleagues made seminal discoveries with them …

In Darwin's and Mendel's times, researchers investigated a wealth of organisms, chosen to
solve particular problems for which they seemed especially well suited. Later, a focus on a …

Developmental enhancers initiate transcription and are fundamental to our understanding of
developmental networks, evolution and disease. Despite their importance, the properties …

Linguistic experience affects phonetic perception. However, the critical period during which
experience affects perception and the mechanism responsible for these effects are …

Forward genetic screens in model organisms have provided important insights into
numerous aspects of development, physiology and pathology. With the availability of …