Carbapenem-resistant Acinetobacter baumannii-calcoaceticus complex (CRAB) is one of
the top-priority pathogens for new antibiotic development. Unlike other antibiotic-resistant …

Antimicrobial resistance has become one of the greatest threats to public health, with rising
resistance to carbapenems being a particular concern due to the lack of effective and safe …

The progressive increase in antibiotic resistance in recent decades calls for urgent
development of new antibiotics and antibiotic stewardship programs to help select …

Eravacycline (Xerava™), a novel fully synthetic fluorocycline, consists of the tetracyclic core
scaffold with unique modifications in the tetracyclic D ring; consequently, it exhibits potent in …

Eravacycline (ERV), formerly known as TP‐434, is a novel tetracycline (TET) antibiotic that
exhibits in vitro activity against various gram‐positive, gram‐negative aerobic and anaerobic …

Omadacycline, a novel aminomethylcycline with in vitro activity against Gram-positive and-
negative organisms, including Streptococcus pneumoniae and Haemophilus influenzae, is …

There is currently an increase in the emergence of multidrug-resistant bacteria (MDR)
worldwide, requiring the development of novel antibiotics. However, it is not only the choice …

Background Minocycline displays high susceptibility rates against Stenotrophomonas
maltophilia at the current breakpoint of 4 mg/L. However, no pharmacodynamic data are …

The emergence of multidrug-resistant (MDR) Gram-negative bacteria has become a global
problem. Among MDR Gram-negative bacteria, carbapenem-resistant Enterobacteriaceae …

Objectives To determine the in vitro activities of novel and comparator antibiotics against
Gram-negative bacteria (GNB) in Taiwan. Methods Isolates of Escherichia coli (n= 335) …