Apitherapy (using bee products) has gained broad recognition in cancer therapeutics
globally. Honeybee venom has a broad range of biological potential, and its utilization is …

As a naturally occurring cytolytic peptide, melittin (MLT) not only exhibits a potent direct
tumor cell-killing effect but also possesses various immunomodulatory functions. MLT shows …

Antimicrobial peptides (AMPs) are natural biopolymers in the host defense system. AMPs
display multiple functions against bacterial, fungal, and viral infection, as well as anticancer …

Therapeutic protein, represented by antibodies, is of increasing interest in human medicine.
However, clinical translation of therapeutic protein is still largely hindered by different …

Viruses are known to infect most types of organisms. In humans, they can cause several
diseases that range from mild to severe. Although many antiviral therapies have been …

In recent decades, bioactive peptides have been gaining recognition in various biomedical
areas, such as intracellular drug delivery (cell-penetrating peptides, CPPs) or anti-infective …

HCC is the most common fatal malignancy. Although surgical resection is the primary
treatment strategy, most patients are not eligible for resection due to tumor heterogeneity …

Melittin (MLT), a peptide containing 26 amino acids, is a key constituent of bee venom. It
comprises∼ 40%–60% of the venom's dry weight and is the main pricing index for bee …

In this study, we explore the interactions between melittin, a cationic antimicrobial peptide,
and model lipid membranes composed of the negatively charged phospholipids 1, 2 …

Ciprofloxacin has been used to replace tryptophan at positions 3 and 6 in the antimicrobial
peptide (AMP) Bac8c. Bac8c (Cip3, 6) showed comparable antimicrobial activity but …