Biosynthesis of polyketide synthase extender units
YA Chan, AM Podevels, BM Kevany… - Natural product …, 2009 - pubs.rsc.org
Biosynthesis of polyketide synthase extender units - Natural Product Reports (RSC Publishing)
DOI:10.1039/B801658P Royal Society of Chemistry View PDF VersionPrevious ArticleNext …
DOI:10.1039/B801658P Royal Society of Chemistry View PDF VersionPrevious ArticleNext …
Malonate metabolism: biochemistry, molecular biology, physiology, and industrial application
YS Kim - BMB Reports, 2002 - koreascience.kr
Malonate is a three-carbon dicarboxylic acid. It is well known as a competitive inhibitor of
succinate dehydrogenase. It occurs naturally in biological systems, such as legumes and …
succinate dehydrogenase. It occurs naturally in biological systems, such as legumes and …
The 1.75 Å crystal structure of acetyl-CoA synthetase bound to adenosine-5 '-propylphosphate and coenzyme A
Acetyl-coenzyme A synthetase catalyzes the two-step synthesis of acetyl-CoA from acetate,
ATP, and CoA and belongs to a family of adenylate-forming enzymes that generate an acyl …
ATP, and CoA and belongs to a family of adenylate-forming enzymes that generate an acyl …
Arabidopsis contains a large superfamily of acyl-activating enzymes. Phylogenetic and biochemical analysis reveals a new class of acyl-coenzyme A synthetases
Acyl-activating enzymes are a diverse group of proteins that catalyze the activation of many
different carboxylic acids, primarily through the formation of a thioester bond. This group of …
different carboxylic acids, primarily through the formation of a thioester bond. This group of …
Characterization of the Propionyl-CoA Synthetase (PrpE) Enzyme of Salmonella enterica: Residue Lys592 Is Required for Propionyl-AMP Synthesis
The propionyl-CoA synthetase (PrpE) enzyme of Salmonella enterica catalyzes the first step
of propionate catabolism, ie, the activation of propionate to propionyl-CoA. The PrpE …
of propionate catabolism, ie, the activation of propionate to propionyl-CoA. The PrpE …
Validation of RetroPath, a computer‐aided design tool for metabolic pathway engineering
Metabolic engineering has succeeded in biosynthesis of numerous commodity or high value
compounds. However, the choice of pathways and enzymes used for production was many …
compounds. However, the choice of pathways and enzymes used for production was many …
Transcriptomic Studies of the Effect of nod Gene-Inducing Molecules in Rhizobia: Different Weapons, One Purpose
Simultaneous quantification of transcripts of the whole bacterial genome allows the analysis
of the global transcriptional response under changing conditions. RNA-seq and microarrays …
of the global transcriptional response under changing conditions. RNA-seq and microarrays …
Identification of 4‐coumarate: coenzyme A ligase (4CL) substrate recognition domains
coumarate: CoA ligase (4CL), the last enzyme of the general phenylpropanoid pathway,
provides precursors for the biosynthesis of a large variety of plant natural products. 4 CL …
provides precursors for the biosynthesis of a large variety of plant natural products. 4 CL …
Mutagenesis evidence that the partial reactions of firefly bioluminescence are catalyzed by different conformations of the luciferase C-terminal domain
BR Branchini, TL Southworth, MH Murtiashaw… - Biochemistry, 2005 - ACS Publications
Firefly luciferase catalyzes two sequential partial reactions resulting in the emission of light.
The enzyme first catalyzes the adenylation of substrate luciferin with Mg-ATP followed by the …
The enzyme first catalyzes the adenylation of substrate luciferin with Mg-ATP followed by the …
Synthesis of adenylated molybdopterin: an essential step for molybdenum insertion
The molybdenum cofactor (Moco) is part of the active site of all molybdenum (Mo)-
dependent enzymes, except nitrogenase. Moco consists of molybdopterin (MPT), a …
dependent enzymes, except nitrogenase. Moco consists of molybdopterin (MPT), a …