Applications of brain organoids in neurodevelopment and neurological diseases
N Sun, X Meng, Y Liu, D Song, C Jiang… - Journal of Biomedical …, 2021 - Springer
A brain organoid is a self-organizing three-dimensional tissue derived from human
embryonic stem cells or pluripotent stem cells and is able to simulate the architecture and …
embryonic stem cells or pluripotent stem cells and is able to simulate the architecture and …
Revealing the clinical potential of high-resolution organoids
The symbiotic interplay of organoid technology and advanced imaging strategies yields
innovative breakthroughs in research and clinical applications. Organoids, intricate three …
innovative breakthroughs in research and clinical applications. Organoids, intricate three …
Neural complexity is increased after low doses of LSD, but not moderate to high doses of oral THC or methamphetamine
CH Murray, J Frohlich, CJ Haggarty, I Tare… - …, 2024 - nature.com
Neural complexity correlates with one's level of consciousness. During coma, anesthesia,
and sleep, complexity is reduced. During altered states, including after lysergic acid …
and sleep, complexity is reduced. During altered states, including after lysergic acid …
Cognitive deficits in methamphetamine addiction: Independent contributions of dependence and intelligence
RE Fitzpatrick, AJ Rubenis, DI Lubman… - Drug and alcohol …, 2020 - Elsevier
Background Methamphetamine's effects on brain function have been associated with
cognitive deficits, which have a negative impact on clinical outcomes. However, it remains …
cognitive deficits, which have a negative impact on clinical outcomes. However, it remains …
Potential brain recovery of frontostriatal circuits in heroin users after prolonged abstinence: A preliminary study
L Lu, W Yang, X Zhang, F Tang, Y Du, L Fan… - Journal of Psychiatric …, 2022 - Elsevier
Neuroscientists have devoted efforts to explore potential brain recovery after prolonged
abstinence in heroin users (HU). However, not much is known about whether frontostriatal …
abstinence in heroin users (HU). However, not much is known about whether frontostriatal …
Alterations in the brain functional network of abstinent male individuals with methamphetamine use disorder
D Luo, W He, D Shen, B Tang, H Tao, Q Tang… - Cerebral …, 2024 - academic.oup.com
Methamphetamine is a highly addictive psychostimulant drug that is abused globally and is
a serious threat to health worldwide. Unfortunately, the specific mechanism underlying …
a serious threat to health worldwide. Unfortunately, the specific mechanism underlying …
Impairments in the default mode and executive networks in methamphetamine users during short-term abstinence
M Gong, Y Shen, W Liang, Z Zhang, C He… - … Journal of General …, 2022 - Taylor & Francis
Purpose Methamphetamine use may cause severe neurotoxicity and cognitive impairment,
leading to addiction, overdose, and high rates of relapse. However, few studies have …
leading to addiction, overdose, and high rates of relapse. However, few studies have …
A reinforcement learning model with choice traces for a progressive ratio schedule
K Ihara, Y Shikano, S Kato, S Yagishita… - Frontiers in Behavioral …, 2024 - frontiersin.org
The progressive ratio (PR) lever-press task serves as a benchmark for assessing goal-
oriented motivation. However, a well-recognized limitation of the PR task is that only a single …
oriented motivation. However, a well-recognized limitation of the PR task is that only a single …
Methamphetamine enhances neural activation during anticipation of loss in the monetary incentive delay task
H Molla, S Keedy, J DeBrosse… - Cerebral Cortex …, 2023 - academic.oup.com
Stimulants like methamphetamine (MA) affect motivated behaviors via actions on circuits
mediating mood, attention, and reward. Few studies examined the effects of single doses of …
mediating mood, attention, and reward. Few studies examined the effects of single doses of …
Enhanced brain network flexibility by physical exercise in female methamphetamine users
X Qi, Y Wang, Y Lu, Q Zhao, Y Chen, C Zhou… - Cognitive …, 2022 - Springer
Methamphetamine (MA) abuse is increasing worldwide, and evidence indicates that MA
causes degraded cognitive functions such as executive function, attention, and flexibility …
causes degraded cognitive functions such as executive function, attention, and flexibility …