Synchronization of biological clock neurons by light and peripheral feedback systems promotes circadian rhythms and health
A Ramkisoensing, JH Meijer - Frontiers in neurology, 2015 - frontiersin.org
In mammals, the suprachiasmatic nucleus (SCN) functions as a circadian clock that drives
24-h rhythms in both physiology and behavior. The SCN is a multicellular oscillator in which …
24-h rhythms in both physiology and behavior. The SCN is a multicellular oscillator in which …
Ion channels controlling circadian rhythms in suprachiasmatic nucleus excitability
JRM Harvey, AE Plante… - Physiological …, 2020 - journals.physiology.org
Animals synchronize to the environmental day-night cycle by means of an internal circadian
clock in the brain. In mammals, this timekee** mechanism is housed in the …
clock in the brain. In mammals, this timekee** mechanism is housed in the …
GABA-mediated repulsive coupling between circadian clock neurons in the SCN encodes seasonal time
The mammalian suprachiasmatic nucleus (SCN) forms not only the master circadian clock
but also a seasonal clock. This neural network of∼ 10,000 circadian oscillators encodes …
but also a seasonal clock. This neural network of∼ 10,000 circadian oscillators encodes …
[HTML][HTML] Phosphoregulation of the Na–K–2Cl and K–Cl cotransporters by the WNK kinases
KT Kahle, J Rinehart, RP Lifton - … et Biophysica Acta (BBA)-Molecular Basis …, 2010 - Elsevier
Precise regulation of the intracellular concentration of chloride [Cl−] i is necessary for proper
cell volume regulation, transepithelial transport, and GABA neurotransmission. The Na–K …
cell volume regulation, transepithelial transport, and GABA neurotransmission. The Na–K …
The dynamics of GABA signaling: revelations from the circadian pacemaker in the suprachiasmatic nucleus
Virtually every neuron within the suprachiasmatic nucleus (SCN) communicates via
GABAergic signaling. The extracellular levels of GABA within the SCN are determined by a …
GABAergic signaling. The extracellular levels of GABA within the SCN are determined by a …
Differential chloride homeostasis in the spinal dorsal horn locally shapes synaptic metaplasticity and modality-specific sensitization
GABAA/glycine-mediated neuronal inhibition critically depends on intracellular chloride
(Cl−) concentration which is mainly regulated by the K+-Cl− co-transporter 2 (KCC2) in the …
(Cl−) concentration which is mainly regulated by the K+-Cl− co-transporter 2 (KCC2) in the …
Daily and seasonal adaptation of the circadian clock requires plasticity of the SCN neuronal network
JH Meijer, S Michel, HT VanderLeest… - European Journal of …, 2010 - Wiley Online Library
Circadian rhythms are an essential property of many living organisms, and arise from an
internal pacemaker, or clock. In mammals, this clock resides in the suprachiasmatic nucleus …
internal pacemaker, or clock. In mammals, this clock resides in the suprachiasmatic nucleus …
Role of GABA in the regulation of the central circadian clock of the suprachiasmatic nucleus
In mammals, circadian rhythms, such as sleep/wake cycles, are regulated by the central
circadian clock located in the suprachiasmatic nucleus (SCN) of the hypothalamus. The …
circadian clock located in the suprachiasmatic nucleus (SCN) of the hypothalamus. The …
Collective timekee** among cells of the master circadian clock
JA Evans - Journal of Endocrinology, 2016 - joe.bioscientifica.com
Maternal vascular adaptation to pregnancy is critically important to expand the capacity for
blood flow through the uteroplacental unit to meet the needs of the develo** fetus. Failure …
blood flow through the uteroplacental unit to meet the needs of the develo** fetus. Failure …
The balance between gluco-and mineralo-corticoid action critically determines inflammatory adipocyte responses
J Hoppmann, N Perwitz, B Meier… - Journal of …, 2010 - joe.bioscientifica.com
This study was conducted to evaluate the responsiveness of human nonpregnant
myometrium to endothelin 1 (ET1)(10 (-10) M-10 (-6) M) and KCl (80 mM) in relation to the …
myometrium to endothelin 1 (ET1)(10 (-10) M-10 (-6) M) and KCl (80 mM) in relation to the …