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Cannabidiol for neurodegenerative disorders: A comprehensive review
Despite the significant advances in neurology, the cure for neurodegenerative conditions
remains a formidable task to date. Among various factors arising from the complex etiology …
remains a formidable task to date. Among various factors arising from the complex etiology …
Role of calcium modulation in the pathophysiology and treatment of Alzheimer's disease
D Baracaldo-Santamaría, SS Avendaño-Lopez… - International journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a chronic neurodegenerative disease and the most frequent
cause of progressive dementia in senior adults. It is characterized by memory loss and …
cause of progressive dementia in senior adults. It is characterized by memory loss and …
Hypoxia, oxidative stress, and inflammation: three faces of neurodegenerative diseases
A Merelli, M Repetto, A Lazarowski… - Journal of Alzheimer's …, 2021 - journals.sagepub.com
The cerebral hypoxia-ischemia can induce a wide spectrum of biologic responses that
include depolarization, excitotoxicity, oxidative stress, inflammation, and apoptosis, and …
include depolarization, excitotoxicity, oxidative stress, inflammation, and apoptosis, and …
[HTML][HTML] Therapeutic potential of cannabis: a comprehensive review of current and future applications
Historically, cannabis has been valued for its pain-relieving, anti-inflammatory, and calming
properties. Ancient civilizations like the Egyptians, Greeks, and Chinese medicines …
properties. Ancient civilizations like the Egyptians, Greeks, and Chinese medicines …
Therapeutic potential of vital transcription factors in Alzheimer's and Parkinson's disease with particular emphasis on transcription factor EB mediated autophagy
Autophagy is an important cellular self-digestion and recycling pathway that helps in
maintaining cellular homeostasis. Dysregulation at various steps of the autophagic and …
maintaining cellular homeostasis. Dysregulation at various steps of the autophagic and …
Endocannabinoid system: chemical characteristics and biological activity
B Rezende, AKN Alencar, GF de Bem… - Pharmaceuticals, 2023 - mdpi.com
The endocannabinoid system (eCB) has been studied to identify the molecular structures
present in Cannabis sativa. eCB consists of cannabinoid receptors, endogenous ligands …
present in Cannabis sativa. eCB consists of cannabinoid receptors, endogenous ligands …
Modulation of oxidative stress and Neuroinflammation by Cannabidiol (CBD): promising targets for the treatment of Alzheimer's disease
JP Hickey, AE Collins, ML Nelson, H Chen… - Current Issues in …, 2024 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease and the most
common form of dementia globally. Although the direct cause of AD remains under debate …
common form of dementia globally. Although the direct cause of AD remains under debate …
Cannabinoids modulate the microbiota–gut–brain axis in HIV/SIV infection by reducing neuroinflammation and dysbiosis while concurrently elevating …
M McDew-White, E Lee, LS Premadasa… - Journal of …, 2023 - Springer
Background Although the advent of combination anti-retroviral therapy (cART) has
transformed HIV into a manageable chronic disease, an estimated 30–50% of people living …
transformed HIV into a manageable chronic disease, an estimated 30–50% of people living …
[HTML][HTML] Cannabis sativa and cannabidiol: a therapeutic strategy for the treatment of neurodegenerative diseases?
This work is a literature review, presenting the current state of the use of cannabinoids on
neurodegenerative diseases. The emphasis is on Parkinson's (PD) and Alzheimer's (AD) …
neurodegenerative diseases. The emphasis is on Parkinson's (PD) and Alzheimer's (AD) …
Novel cannabidiol− carbamate hybrids as selective BuChE inhibitors: Docking-based fragment reassembly for the development of potential therapeutic agents against …
X Jiang, Z Zhang, J Zuo, C Wu, L Zha, Y Xu… - European journal of …, 2021 - Elsevier
Cannabidiol (CBD) and rivastigmine have been launched as drugs for treating dementia
and cholinesterases (ChEs) are ideal drug targets. This study focused on develo** novel …
and cholinesterases (ChEs) are ideal drug targets. This study focused on develo** novel …