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Regulation of actin bundle mechanics and structure by intracellular environmental factors
The mechanical and structural properties of actin cytoskeleton drive various cellular
processes, including structural support of the plasma membrane and cellular motility. Actin …
processes, including structural support of the plasma membrane and cellular motility. Actin …
Optical tweezers approaches for probing multiscale protein mechanics and assembly
K Lehmann, M Shayegan, GA Blab… - Frontiers in Molecular …, 2020 - frontiersin.org
Multi-step assembly of individual protein building blocks is key to the formation of essential
higher-order structures inside and outside of cells. Optical tweezers is a technique well …
higher-order structures inside and outside of cells. Optical tweezers is a technique well …
Actin filament alignment causes mechanical hysteresis in cross-linked networks
Cells dynamically control their material properties through remodeling of the actin
cytoskeleton, an assembly of cross-linked networks and bundles formed from the biopolymer …
cytoskeleton, an assembly of cross-linked networks and bundles formed from the biopolymer …
Architectural dynamics of CaMKII-actin networks
Calcium-calmodulin-dependent kinase II (CaMKII) has an important role in dendritic spine
remodeling upon synaptic stimulation. Using fluorescence video microscopy and image …
remodeling upon synaptic stimulation. Using fluorescence video microscopy and image …
Stiffening and inelastic fluidization in vimentin intermediate filament networks
Intermediate filaments are cytoskeletal proteins that are key regulators of cell mechanics, a
role which is intrinsically tied to their hierarchical structure and their unique ability to …
role which is intrinsically tied to their hierarchical structure and their unique ability to …
Cell migration regulated by spatially controlled stiffness inside composition‐tunable three‐dimensional dextran hydrogels
X Yin, X Zhu, Z Wang - Advanced Materials Interfaces, 2021 - Wiley Online Library
Stiffness of the extracellular matrix plays an important role in regulating cell migration. In this
paper, two types of 3D dextran hydrogel, with the stiffness distributed homogeneously and …
paper, two types of 3D dextran hydrogel, with the stiffness distributed homogeneously and …
[HTML][HTML] Actin stress fibers response and adaptation under stretch
R Bernal, M Van Hemelryck, B Gurchenkov… - International Journal of …, 2022 - mdpi.com
One of the many effects of soft tissues under mechanical solicitation in the cellular damage
produced by highly localized strain. Here, we study the response of peripheral stress fibers …
produced by highly localized strain. Here, we study the response of peripheral stress fibers …
Biomechanical response of cancer stem cells to low-intensity ultrasound
Y Yang, M Du, J Yu, Z Chen - Journal of …, 2023 - asmedigitalcollection.asme.org
The presence of stem cells in cancer may increase the chances of drug resistance and
invasiveness. Low-intensity ultrasound (LIUS) can regulate the biological and mechanical …
invasiveness. Low-intensity ultrasound (LIUS) can regulate the biological and mechanical …
Force production by a bundle of growing actin filaments is limited by its mechanical properties
Bundles of actin filaments are central to a large variety of cellular structures such as
filopodia, stress fibers, cytokinetic rings, and focal adhesions. The mechanical properties of …
filopodia, stress fibers, cytokinetic rings, and focal adhesions. The mechanical properties of …
Crowding tunes the organization and mechanics of actin bundles formed by crosslinking proteins
Fascin and α‐actinin form higher‐ordered actin bundles that mediate numerous cellular
processes including cell morphogenesis and movement. While it is understood crosslinked …
processes including cell morphogenesis and movement. While it is understood crosslinked …