Recent studies of the three eukaryotic transcription machineries revealed that all initiation
complexes share a conserved core. This core consists of the RNA polymerase (I, II, or III), the …

A key step in retrieving the information stored in the complex genomes of eukaryotes
involves the identification of transcription units and, more specifically, the recognition of …

In eukaryotes, transcription is carried out by three different RNA polymerases, RNA
polymerases I, II, and III, each of which is dedicated to the transcription of different sets of …

Recent studies on RNA polymerase III (pol III) gene transcription have provided a new
awareness of the molecular complexity of this process. Fortunately, while the number of …

Abstract African Swine Fever Virus is a Nucleo-Cytoplasmic Large DNA Virus that causes an
incurable haemorrhagic fever in pigs with a high impact on global food security. ASFV …

Molecular matchmakers are a class of proteins that use the energy released from the
hydrolysis of adenosine triphosphate to cause a conformational change in one or both …

The Saccharomyces cerevisiae RNA polymerase Ill transcription factor (TF) IIIB has been
assembled from three components. An assembly pathway of these polypeptides, which …

We have determined that TPD3, a gene previously identified in a screen for mutants
defective in tRNA biosynthesis, most likely encodes the A regulatory subunit of the major …

Transcription initiation at RNA polymerase III promoters requires transcription factor IIIB
(TFIIIB), an activity that binds to RNA polymerase III promoters, generally through protein …

A suppressor gene was identified, which in high copy number rescues a temperature-
sensitive mutation in yeast TATA-binding protein (TBP). Suppression was allele specific …