Background Aging is associated with a decline in cognitive and physical functions and
various geriatric diseases, such as cardiovascular and neurodegenerative diseases …

Neural stem/progenitor cell (NSPC) self-renewal and differentiation in the develo** and
the adult brain are controlled by extra-cellular signals and by the inherent competence of …

Traumatic brain injury (TBI) initiates molecular and cellular pathologies that underlie post-
injury morbidities, including hippocampus-related memory decline and epileptogenesis …

Neural stem progenitor cells (NSPCs) from E13. 5 mouse embryos can be maintained in
culture under proliferating conditions. Upon growth-factor removal, they may differentiate …

Long-term maintenance of the adult neurogenic niche depends on proper regulation of entry
and exit from quiescence. Neural stem cell (NSC) transition from quiescence to activation is …

Mutations of Fused in sarcoma (FUS), a ribonucleoprotein involved in RNA metabolism,
have been found associated with both familial and sporadic cases of amyotrophic lateral …

Adult neurogenesis declines with aging due to the depletion and functional impairment of
neural stem/progenitor cells (NSPC s). An improved understanding of the underlying …

Axonal regeneration has been the research focus in the field of clinical treatment for spinal
cord injury (SCI). The growth and extension of neuronal axons is a dynamic biological …

In rodents, well characterized neurogenic niches of the adult brain, such as the
subventricular zone of the lateral ventricles and the subgranular zone of the hippocampus …

Nervous system development involves proliferation and cell specification of progenitor cells
into neurons and glial cells. Unveiling how this complex process is orchestrated under …