Repair strategies and bioactive functional materials for intervertebral disc

D Wu, G Li, X Zhou, W Zhang, H Liang… - Advanced Functional …, 2022 - Wiley Online Library
Intervertebral disc (IVD) degeneration is the leading cause of low back pain, which
represents a highly prevalent chronic aging‐associated disorder with a large socio …

Pre‐clinical and clinical applications of thermoreversible hydrogels in biomedical engineering: a review

AP Constantinou, TK Georgiou - Polymer International, 2021 - Wiley Online Library
Thermoreversible polymer hydrogels (TRGs) are physical aqueous networks triggered by
temperature that find potential applications in tissue engineering (TE) and drug/gene …

Regulating bacterial behavior within hydrogels of tunable viscoelasticity

S Bhusari, S Sankaran, A Del Campo - Advanced Science, 2022 - Wiley Online Library
Engineered living materials (ELMs) are a new class of materials in which living organism
incorporated into diffusive matrices uptake a fundamental role in material's composition and …

[HTML][HTML] Delivery of coenzyme Q10 loaded micelle targets mitochondrial ROS and enhances efficiency of mesenchymal stem cell therapy in intervertebral disc …

J Sun, F Yang, L Wang, H Yu, Z Yang, J Wei, K Vasilev… - Bioactive Materials, 2023 - Elsevier
Stem cell transplantation has been proved a promising therapeutic instrument in
intervertebral disc degeneration (IVDD). However, the elevation of oxidative stress in the …

Injectable hydrogels based on inter-polyelectrolyte interactions between hyaluronic acid, gelatin, and cationic cellulose nanocrystals

C Warwar Damouny, P Martin, G Vasilyev… - …, 2022 - ACS Publications
The present work dealt with the development of physically cross-linked injectable hydrogels
with potential applications in tissue engineering. The hydrogels were composed of a ternary …

“Smart” Stimuli‐responsive Injectable Gels for Bone Tissue Engineering Application

H Li, Z Hao, S Zhang, B Li, Y Wang… - Macromolecular …, 2023 - Wiley Online Library
Bone grafting, as the current gold‐standard for large scaled bone damage of various
causes, has faced challenges from both the source and appliance. Emerging new tissue …

[HTML][HTML] Injectable Biomimetic Gels for Biomedical Applications

H Omidian, RL Wilson, S Dey Chowdhury - Biomimetics, 2024 - mdpi.com
Biomimetic gels are synthetic materials designed to mimic the properties and functions of
natural biological systems, such as tissues and cellular environments. This manuscript …

Controlling spatiotemporal mechanics of globular protein-polymer hydrogel via metal-coordination interactions

A Dutta, G Vasilyev, R Vilensky, E Zussman - Chemical Engineering …, 2024 - Elsevier
Mechanical properties of hydrogels are dependent on their spatial and temporal structural
properties. Several attempts have been made to tune the mechanical properties of …

Additive manufactured self-powered mechanoelectric sensor as the artificial nucleus pulposus for monitoring tissue rehabilitation after discectomy

Y Shi, K Wang, X Feng, S Li, G Li, W Li, W Ke, A Chen… - Nano Energy, 2022 - Elsevier
The capability to monitor the mechanical forces on the intervertebral disc (IVD) after
discectomy could develop personalized rehabilitation strategies to benefit the patients´ …

Aggressive strategies for regenerating intervertebral discs: stimulus-responsive composite hydrogels from single to multiscale delivery systems

X Gao, X Zhang, R Zhang, D Yu, X Chen… - Journal of Materials …, 2022 - pubs.rsc.org
As our research on the physiopathology of intervertebral disc degeneration (IVD
degeneration, IVDD) has advanced and tissue engineering has rapidly evolved, cell …