Rhodium-catalyzed asymmetric C–H functionalization reactions

CX Liu, SY Yin, F Zhao, H Yang, Z Feng, Q Gu… - Chemical …, 2023 - ACS Publications
This review summarizes the advancements in rhodium-catalyzed asymmetric C–H
functionalization reactions during the last two decades. Parallel to the rapidly developed …

Electrochemical late-stage functionalization

Y Wang, S Dana, H Long, Y Xu, Y Li… - Chemical …, 2023 - ACS Publications
Late-stage functionalization (LSF) constitutes a powerful strategy for the assembly or
diversification of novel molecular entities with improved physicochemical or biological …

Enantioselective electrochemical cobalt-catalyzed aryl C–H activation reactions

T von Münchow, S Dana, Y Xu, B Yuan, L Ackermann - Science, 2023 - science.org
Enantioselective redox transformations typically rely on costly transition metals as catalysts
and often stoichiometric amounts of chemical redox agents as well. Electrocatalysis …

An atomically dispersed Mn-photocatalyst for generating hydrogen peroxide from seawater via the water oxidation reaction (WOR)

P Ren, T Zhang, N Jain, HYV Ching… - Journal of the …, 2023 - ACS Publications
In this work, we have fabricated an aryl amino-substituted graphitic carbon nitride (g-C3N4)
catalyst with atomically dispersed Mn capable of generating hydrogen peroxide (H2O2) …

Transition-Metal-Catalyzed, Coordination-Assisted Functionalization of Nonactivated C(sp3)–H Bonds

B Liu, AM Romine, CZ Rubel, KM Engle… - Chemical reviews, 2021 - ACS Publications
Transition-metal-catalyzed, coordination-assisted C (sp3)–H functionalization has
revolutionized synthetic planning over the past few decades as the use of these directing …

Photoactive Metal-to-Ligand Charge Transfer Excited States in 3d6 Complexes with Cr0, MnI, FeII, and CoIII

N Sinha, OS Wenger - Journal of the American Chemical Society, 2023 - ACS Publications
Many coordination complexes and organometallic compounds with the 4d6 and 5d6
valence electron configurations have outstanding photophysical and photochemical …

Late-stage C–H functionalization offers new opportunities in drug discovery

L Guillemard, N Kaplaneris, L Ackermann… - Nature Reviews …, 2021 - nature.com
Over the past decade, the landscape of molecular synthesis has gained major impetus by
the introduction of late-stage functionalization (LSF) methodologies. C–H functionalization …

Late-stage functionalization for improving drug-like molecular properties

NJ Castellino, AP Montgomery, JJ Danon… - Chemical …, 2023 - ACS Publications
The development of late-stage functionalization (LSF) methodologies, particularly C–H
functionalization, has revolutionized the field of organic synthesis. Over the past decade …

C–H activation

T Rogge, N Kaplaneris, N Chatani, J Kim… - Nature Reviews …, 2021 - nature.com
Transition metal-catalysed C–H activation has emerged as an increasingly powerful platform
for molecular syntheses, enabling applications to natural product syntheses, late-stage …

Recent advances in transition-metal-catalyzed carbene insertion to C–H bonds

Y He, Z Huang, K Wu, J Ma, YG Zhou… - Chemical Society Reviews, 2022 - pubs.rsc.org
C–H functionalization has been emerging as a powerful method to establish carbon–carbon
and carbon–heteroatom bonds. Many efforts have been devoted to transition-metal …