Vaccines are needed to protect from SARS-CoV-2, the virus causing COVID-19. Vaccines
that induce large quantities of high affinity virus-neutralizing antibodies may optimally …

Dendritic-cells (DCs) have received considerable attention as potential targets for the
development of anticancer vaccines. DC-based anticancer vaccination relies on patient …

T-cell immunity is important for recovery from COVID-19 and provides heightened immunity
for re-infection. However, little is known about the SARS-CoV-2-specific T-cell immunity in …

Dendritic cell (DC)-based vaccines against cancer have been extensively developed over
the past two decades. Typically DC-based cancer immunotherapy entails loading patient …

Immune checkpoint blockade has proven its efficacy in hypermutated subtypes of metastatic
colorectal cancers (mCRC). Immunogenic potential can also be observed with conventional …

The effects of different SARS-CoV-2 vaccinations and variant infection histories on
imprinting population immunity and their influence on emerging escape mutants remain …

Cytotoxic CD8+ T cells recognize and eliminate infected or malignant cells that present
peptide epitopes derived from intracellularly processed antigens on their surface. However …

Purpose: Treatments with cancer vaccines may be delivered as combination therapies for
better efficacy. Addition of intravesical immunostimulation with bacteria promotes vaccine …

The analysis of antigen-specific T-cell responses has become routine in many laboratories.
Functional T-cell assays like enzyme-linked-immuno-spot (ELISPOT), which depend on …

The dynamic interaction between the CMV virus and host immune response remains
obscure, thus hindering the diagnosis and therapeutic management of patients with HSCT …