Background Alzheimer's disease (AD) is the commonest cause of dementia, with
approximately 5 million new cases occurring annually. Despite decades of research, its …

The α7-nicotinic acetylcholine receptor (α7nAChR) is a key protein in the cholinergic anti-
inflammatory pathway (CAP) that links the nervous and immune systems. Initially, the …

Myocardial infarction (MI) is a coronary artery-related disease and ranks as the leading
cause of sudden death globally. Resveratrol (Res) is a bioactive component and has …

Excessive reactive oxygen species (ROS) generated after myocardial infarction (MI) result in
the oxidative injury in myocardium. Implantation of antioxidant biomaterials, without the use …

Background Oxidative stress and inflammatory reaction play critical roles in acute
myocardial infarction (AMI). Isoliquiritigenin (ISL), a flavonoid monomer extracted from …

In the genesis and progression of cardiovascular diseases involving both innate and
adaptive immune responses, inflammation plays a pivotal and dual role. Studies in …

Background Neutrophil to lymphocyte ratio (NLR) in peripheral blood is established to
correlate with the morbidity and mortality of heart disease patients. We aimed to define the …

Global burden of diseases (GBD) includes non-communicable conditions such as
cardiovascular diseases, cancer and chronic obstructive pulmonary disease. These share …

Background Inflammation and fibrosis play an important role in the pathogenesis of atrial
fibrillation (AF) after myocardial infarction (MI). CTRP9 (C1q/tumor necrosis factor‐related …

Atherosclerosis remains the leading cause of mortality and morbidity worldwide
characterized by the deposition of lipids and fibrous elements in the form of atheroma …