Molecular ratchets and kinetic asymmetry: Giving chemistry direction

S Borsley, DA Leigh… - Angewandte Chemie …, 2024 - Wiley Online Library
Over the last two decades ratchet mechanisms have transformed the understanding and
design of stochastic molecular systems—biological, chemical and physical—in a move away …

Artificial molecular pumps

L Zhang, H Wu, X Li, H Chen, RD Astumian… - Nature Reviews …, 2024 - nature.com
Reflecting on recent progress in bottom-up engineering focused on creating the smallest
devices capable of controlling nanoscale motion, artificial molecular pumps (AMPs) are …

Photoswitchable Imines Drive Dynamic Covalent Systems to Nonequilibrium Steady States

J Wu, JL Greenfield - Journal of the American Chemical Society, 2024 - ACS Publications
Coupling a photochemical reaction to a thermal exchange process can drive the latter to a
nonequilibrium steady state (NESS) under photoirradiation. Typically, systems use separate …

The sugar cube: Network control and emergence in stereoediting reactions

HM Carder, G Occhialini, G Bistoni, C Riplinger… - Science, 2024 - science.org
Stereochemical editing strategies have recently enabled the transformation of readily
accessible substrates into rare and valuable products. Typically, site selectivity is achieved …

Physicochemical Principles of AC Electrosynthesis: Reversible Reactions

YR Poh, Y Kawamata, J Yuen-Zhou - Journal of the American …, 2024 - ACS Publications
Electrolysis integrates renewable energy into chemical manufacturing and is key to
sustainable chemistry. Controlling the waveform beyond direct current (DC) addresses the …

Catalytic resonance theory: the catalytic mechanics of programmable ratchets

MA Murphy, SR Gathmann, R Getman, L Grabow… - Chemical …, 2024 - pubs.rsc.org
Catalytic reaction networks of multiple elementary steps operating under dynamic conditions
via a programmed input oscillation are difficult to interpret and optimize due to reaction …

A Minimalistic Covalent Bond‐Forming Chemical Reaction Cycle that Consumes Adenosine Diphosphate

T Marchetti, BMW Roberts, D Frezzato… - Angewandte …, 2024 - Wiley Online Library
The development of synthetic active matter requires the ability to design materials capable of
harnessing energy from a source to carry out work. Nature achieves this using chemical …

Dynamic Promotion of the Oxygen Evolution Reaction via Programmable Metal Oxides

SR Gathmann, CJ Bartel, LC Grabow… - ACS Energy …, 2024 - ACS Publications
Hydrogen gas is a promising renewable energy storage medium when produced via water
electrolysis, but this process is limited by the sluggish kinetics of the anodic oxygen …

Catalytic resonance theory: forecasting the flow of programmable catalytic loops

MA Murphy, K Noordhoek, SR Gathmann… - Digital …, 2025 - pubs.rsc.org
Chemical transformations on catalyst surfaces occur through series and parallel reaction
pathways. These complex networks and their behavior can be most simply evaluated …

Endergonic synthesis driven by chemical fuelling

E Olivieri, JM Gallagher, A Betts, TW Mrad, DA Leigh - Nature Synthesis, 2024 - nature.com
Spontaneous chemical reactions proceed energetically downhill to either a local or global
minimum, limiting possible transformations to those that are exergonic. Endergonic reactions …