abstract Bronchial asthma is characterized by chronic airway inflammation, which manifests
clinically as variable airway narrowing (wheezes and dyspnea) and cough. Long-standing …

Metabolism of arachidonic acid leads to several families of lipid mediators, including
prostaglandins, thromboxane, leukotrienes, and lipoxins, along two major metabolic …

Asthma is the most common chronic lower respiratory disease in childhood throughout the
world. Several guidelines and/or consensus documents are available to support medical …

Prostaglandins and leukotrienes are potent eicosanoid lipid mediators derived from
phospholipase-released arachidonic acid that are involved in numerous homeostatic …

Asthma is a serious health problem throughout the world. During the past two decades,
many scientific advances have improved our understanding of asthma and ability to manage …

Over the last few decade Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) are the drugs of
choice for treating numerous inflammatory diseases including rheumatoid arthritis. The …

abstract Asthma is characterized by chronic airway inflammation, variable airway narrowing,
and sensory nerve irritation, which manifest as wheezing, dyspnea, chest tightness, and …

Lipoxygenase reactions may initiate the synthesis of a signaling molecule or be involved in
inducing structural or metabolic changes in the cell. For signaling, synthesis of a single fatty …

This review of leukotrienes, which are lipid mediators with a broad array of clinical effects,
and leukotriene receptors considers the biochemical and physiological aspects of these …

Allergic rhinitis, asthma, and atopic eczema are among the commonest causes of chronic ill
health. These diseases are increasing in prevalence, and they add considerably to the …