Gut–skin axis: current knowledge of the interrelationship between microbial dysbiosis and skin conditions

B De Pessemier, L Grine, M Debaere, A Maes… - Microorganisms, 2021 - mdpi.com
The microbiome plays an important role in a wide variety of skin disorders. Not only is the
skin microbiome altered, but also surprisingly many skin diseases are accompanied by an …

CGRP physiology, pharmacology, and therapeutic targets: migraine and beyond

AF Russo, DL Hay - Physiological reviews, 2023 - journals.physiology.org
Calcitonin gene-related peptide (CGRP) is a neuropeptide with diverse physiological
functions. Its two isoforms (α and β) are widely expressed throughout the body in sensory …

Skin acute wound healing: a comprehensive review

L Cañedo-Dorantes… - International journal of …, 2019 - Wiley Online Library
Experimental work of the last two decades has revealed the general steps of the wound
healing process. This complex network has been organized in three sequential and …

Standard classification and pathophysiology of rosacea: the 2017 update by the National Rosacea Society Expert Committee

RL Gallo, RD Granstein, S Kang, M Mannis… - Journal of the American …, 2018 - Elsevier
In 2002, the National Rosacea Society assembled an expert committee to develop the first
standard classification of rosacea. This original classification was intended to be updated as …

[HTML][HTML] Mammalian transient receptor potential TRPA1 channels: from structure to disease

K Talavera, JB Startek, J Alvarez-Collazo… - Physiological …, 2020 - journals.physiology.org
The transient receptor potential ankyrin (TRPA) channels are Ca 2+-permeable nonselective
cation channels remarkably conserved through the animal kingdom. Mammals have only …

Rosacea: part I. Introduction, categorization, histology, pathogenesis, and risk factors

AM Two, W Wu, RL Gallo, TR Hata - Journal of the American Academy of …, 2015 - Elsevier
Rosacea is a chronic inflammatory skin condition that affects approximately 16 million
Americans. Four distinct subtypes of rosacea have been recognized, with transient and …

TRPV1 and TRPA1 in cutaneous neurogenic and chronic inflammation: pro-inflammatory response induced by their activation and their sensitization

O Gouin, K L'herondelle, N Lebonvallet… - Protein & …, 2017 - academic.oup.com
Cutaneous neurogenic inflammation (CNI) is inflammation that is induced (or enhanced) in
the skin by the release of neuropeptides from sensory nerve endings. Clinical manifestations …

Transient receptor potential channels in the vasculature

S Earley, JE Brayden - Physiological reviews, 2015 - journals.physiology.org
The mammalian genome encodes 28 distinct members of the transient receptor potential
(TRP) superfamily of cation channels, which exhibit varying degrees of selectivity for …

Mediators of chronic pruritus in atopic dermatitis: getting the itch out?

NK Mollanazar, PK Smith, G Yosipovitch - Clinical reviews in allergy & …, 2016 - Springer
For centuries, itch was categorized as a submodality of pain. Recent research over the last
decade has led to the realization that itch is in fact a separate and distinct, albeit closely …

New insights into rosacea pathophysiology: a review of recent findings

M Steinhoff, J Schauber, JJ Leyden - Journal of the American Academy of …, 2013 - Elsevier
Rosacea is a common, chronic inflammatory skin disease of poorly understood origin.
Based on its clinical features (flushing, chronic inflammation, fibrosis) and trigger factors, a …