New technologies for analysis of extracellular vesicles
Extracellular vesicles (EVs) are diverse, nanoscale membrane vesicles actively released by
cells. Similar-sized vesicles can be further classified (eg, exosomes, microvesicles) based …
cells. Similar-sized vesicles can be further classified (eg, exosomes, microvesicles) based …
Potential use of exosomes as diagnostic biomarkers and in targeted drug delivery: progress in clinical and preclinical applications
Exosomes are cell-derived vesicles containing heterogeneous active biomolecules such as
proteins, lipids, mRNAs, receptors, immune regulatory molecules, and nucleic acids. They …
proteins, lipids, mRNAs, receptors, immune regulatory molecules, and nucleic acids. They …
Circular RNAs in kidney disease and cancer
Circular RNAs (circRNAs) are a class of endogenously expressed regulatory RNAs with a
single-stranded circular structure. They are generated by back splicing and their expression …
single-stranded circular structure. They are generated by back splicing and their expression …
Preservation and storage stability of extracellular vesicles for therapeutic applications
Abstract Recently, extracellular vesicles (EVs)—including exosomes, microvesicles, and
others—have attracted interest as cell-derived biotherapeutics and drug delivery vehicles for …
others—have attracted interest as cell-derived biotherapeutics and drug delivery vehicles for …
Biological properties of extracellular vesicles and their physiological functions
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …
Standardization of sample collection, isolation and analysis methods in extracellular vesicle research
The emergence of publications on extracellular RNA (exRNA) and extracellular vesicles
(EV) has highlighted the potential of these molecules and vehicles as biomarkers of disease …
(EV) has highlighted the potential of these molecules and vehicles as biomarkers of disease …
Extracellular vesicles in renal disease
D Karpman, A Ståhl, I Arvidsson - Nature Reviews Nephrology, 2017 - nature.com
Extracellular vesicles, such as exosomes and microvesicles, are host cell-derived packages
of information that allow cell–cell communication and enable cells to rid themselves of …
of information that allow cell–cell communication and enable cells to rid themselves of …
Extracellular vesicles: techniques and biomedical applications related to single vesicle analysis
J Zhang, J Wu, G Wang, L He, Z Zheng, M Wu… - ACS …, 2023 - ACS Publications
Extracellular vesicles (EVs) are extensively dispersed lipid bilayer membrane vesicles
involved in the delivery and transportation of molecular payloads to certain cell types to …
involved in the delivery and transportation of molecular payloads to certain cell types to …
Circulating microRNAs as novel biomarkers for diabetes mellitus
C Guay, R Regazzi - Nature Reviews Endocrinology, 2013 - nature.com
Diabetes mellitus is characterized by insulin secretion from pancreatic β cells that is
insufficient to maintain blood glucose homeostasis. Autoimmune destruction of β cells …
insufficient to maintain blood glucose homeostasis. Autoimmune destruction of β cells …
Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes
Background: The healthy vascular endothelium, which forms the barrier between blood and
the surrounding tissues, is known to efficiently respond to stress signals like hypoxia and …
the surrounding tissues, is known to efficiently respond to stress signals like hypoxia and …