Cell membranes contain a large variety of lipid types and are crowded with proteins,
endowing them with the plasticity needed to fulfill their key roles in cell functioning. The …

The Martini model, a coarse-grained force field for biomolecular simulations, has found a
broad range of applications since its release a decade ago. Based on a building block …

Ten years ago, we wrote a Review on lipid rafts and signalling in the launch issue of Nature
Reviews Molecular Cell Biology. At the time, this field was suffering from ambiguous …

Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

Biomembranes are exceptionally crowded with proteins with typical protein-to-lipid ratios
being around 1∶ 50− 1∶ 100. Protein crowding has a decisive role in lateral membrane …

Lipid membranes can spontaneously organize their components into domains of different
sizes and properties. The organization of membrane lipids into nanodomains might …

β-Barrel outer membrane proteins (OMPs) represent the major proteinaceous component of
the outer membrane (OM) of Gram-negative bacteria. These proteins perform key roles in …

The dynamics of constituents and the surface response of cellular membranes—also in
connection to the binding of various particles and macromolecules to the membrane—are …

Ever since technologies enabled the characterization of eukaryotic plasma membranes,
heterogeneities in the distributions of its constituents were observed. Over the years this led …

The cell nucleus is best known as the container of the genome. Its envelope provides a
barrier for passive macromolecule diffusion, which enhances the control of gene expression …