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[PDF][PDF] Endocrine-disrupting chemicals in ovarian function: effects on steroidogenesis, metabolism and nuclear receptor signaling
Endocrine-disrupting chemicals (EDCs) are exogenous agents with the ability to interfere
with processes regulated by endogenous hormones. One such process is female …
with processes regulated by endogenous hormones. One such process is female …
Molecular pathogenesis of granulosa cell tumors of the ovary
S Jamieson, PJ Fuller - Endocrine reviews, 2012 - academic.oup.com
Granulosa cell tumors of the ovary (GCT) comprise a distinct subset of ovarian cancers that
account for approximately 5% of all ovarian malignancies. They are thought to arise from …
account for approximately 5% of all ovarian malignancies. They are thought to arise from …
Bisphenol a exposure causes meiotic aneuploidy in the female mouse
Background: There is increasing concern that exposure to man-made substances that mimic
endogenous hormones may adversely affect mammalian reproduction. Although a variety of …
endogenous hormones may adversely affect mammalian reproduction. Although a variety of …
GPR30 does not mediate estrogenic responses in reproductive organs in mice
C Otto, I Fuchs, G Kauselmann, H Kern… - Biology of …, 2009 - academic.oup.com
The G protein-coupled receptor Gpr30 (Gper) was recently claimed to bind to estradiol and
to activate cytoplasmic signal transduction pathways in response to estradiol. However …
to activate cytoplasmic signal transduction pathways in response to estradiol. However …
Neonatal exposure to bisphenol A reduces the pool of primordial follicles in the rat ovary
HA Rodríguez, N Santambrosio, CG Santamaría… - Reproductive …, 2010 - Elsevier
We evaluated whether exposure to bisphenol A (BPA) disrupts neonatal follicle
development in rats. From postnatal day 1 (PND1) to PND7, pups received corn oil (control) …
development in rats. From postnatal day 1 (PND1) to PND7, pups received corn oil (control) …
Environmental xenobiotics and nuclear receptors—Interactions, effects and in vitro assessment
A group of intracellular nuclear receptors is a protein superfamily including arylhydrocarbon
AhR, estrogen ER, androgen AR, thyroid TR and retinoid receptors RAR/RXR as well as …
AhR, estrogen ER, androgen AR, thyroid TR and retinoid receptors RAR/RXR as well as …
Recruitment and development of the follicle; the roles of the transforming growth factor-β superfamily
Peripheral endocrine hormones and local paracrine and autocrine factors contribute, in a
coordinated fashion, to the processes of recruitment, development or atresia, selection and …
coordinated fashion, to the processes of recruitment, development or atresia, selection and …
Proteomic comparison of detergent-extracted sperm proteins from bulls with different fertility indexes
O D'Amours, G Frenette, M Fortier, P Leclerc… - …, 2010 - rep.bioscientifica.com
In mammals, suppressor of cytokine signalling (CISH, SOCS1 to SOCS7) factors control
signalling pathways involved in the regulation of numerous physiological processes …
signalling pathways involved in the regulation of numerous physiological processes …
The role of the aryl hydrocarbon receptor in the female reproductive system
In recent years, many studies have emphasized how changes in aryl hydrocarbon receptor
(AHR)-mediated gene expression result in biological effects, raising interest in this receptor …
(AHR)-mediated gene expression result in biological effects, raising interest in this receptor …
Estrogen dependent signaling in reproductive tissues–a role for estrogen receptors and estrogen related receptors
Estrogens play a fundamental role in the development and normal physiological function of
multiple tissue systems and have been implicated in the ontogeny of cancers. The biological …
multiple tissue systems and have been implicated in the ontogeny of cancers. The biological …