Lipids and lipid derivatives for RNA delivery
RNA-based therapeutics have shown great promise in treating a broad spectrum of
diseases through various mechanisms including knockdown of pathological genes …
diseases through various mechanisms including knockdown of pathological genes …
The biological applications of DNA nanomaterials: current challenges and future directions
W Ma, Y Zhan, Y Zhang, C Mao, X **e… - Signal transduction and …, 2021 - nature.com
DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …
biological applications as driven by DNA nanotechnology in the past decades, including …
DNA functional materials assembled from branched DNA: design, synthesis, and applications
Y Dong, C Yao, Y Zhu, L Yang, D Luo… - Chemical Reviews, 2020 - ACS Publications
DNA is traditionally known as a central genetic biomolecule in living systems. From an
alternative perspective, DNA is a versatile molecular building-block for the construction of …
alternative perspective, DNA is a versatile molecular building-block for the construction of …
Nuclease resistance of DNA nanostructures
AR Chandrasekaran - Nature Reviews Chemistry, 2021 - nature.com
DNA nanotechnology has progressed from proof-of-concept demonstrations of structural
design towards application-oriented research. As a natural material with excellent self …
design towards application-oriented research. As a natural material with excellent self …
Rationally engineered nucleic acid architectures for biosensing applications
Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …
Genetically encoded DNA origami for gene therapy in vivo
X Wu, C Yang, H Wang, X Lu, Y Shang… - Journal of the …, 2023 - ACS Publications
DNA origami has played an important role in various biomedical applications, including
biosensing, bioimaging, and drug delivery. However, the function of the long DNA scaffold …
biosensing, bioimaging, and drug delivery. However, the function of the long DNA scaffold …
pH-and miRNA-responsive DNA-tetrahedra/metal–organic framework conjugates: functional sense-and-treat carriers
The synthesis of stimuli-responsive hybrid structures composed of drug-loaded UiO-66
metal–organic framework nanoparticles, NMOFs, locked by DNA tetrahedra gates is …
metal–organic framework nanoparticles, NMOFs, locked by DNA tetrahedra gates is …
DNA tetrahedra modules as versatile optical sensing platforms for multiplexed analysis of miRNAs, endonucleases, and aptamer–ligand complexes
The sensing modules for analyzing miRNAs or the endonucleases consist of tetrahedra
functionalized with three different fluorophore–quencher pairs in spatially quenched …
functionalized with three different fluorophore–quencher pairs in spatially quenched …
Metal‐Modified Nucleic Acids: Metal‐Mediated Base Pairs, Triples, and Tetrads
The incorporation of metal ions into nucleic acids by means of metal‐mediated base pairs
represents a promising and prominent strategy for the site‐specific decoration of these self …
represents a promising and prominent strategy for the site‐specific decoration of these self …
Advances in regenerative medicine applications of tetrahedral framework nucleic acid-based nanomaterials: an expert consensus recommendation
Y Lin, Q Li, L Wang, Q Guo, S Liu, S Zhu… - International Journal of …, 2022 - nature.com
With the emergence of DNA nanotechnology in the 1980s, self-assembled DNA
nanostructures have attracted considerable attention worldwide due to their inherent …
nanostructures have attracted considerable attention worldwide due to their inherent …