[HTML][HTML] Supramolecular engineering of hydrogels for drug delivery

S Bernhard, MW Tibbitt - Advanced Drug Delivery Reviews, 2021 - Elsevier
Supramolecular binding motifs are increasingly employed in the design of biomaterials. The
ability to rationally engineer specific yet reversible associations into polymer networks with …

Role of hydrophobic associations in self-healing hydrogels based on amphiphilic polysaccharides

M Nichifor - Polymers, 2023 - mdpi.com
Self-healing hydrogels have the ability to recover their original properties after the action of
an external stress, due to presence in their structure of reversible chemical or physical cross …

Building block properties govern granular hydrogel mechanics through contact deformations

DB Emiroglu, A Bekcic, D Dranseike, X Zhang… - Science …, 2022 - science.org
Granular hydrogels have been increasingly exploited in biomedical applications, including
wound healing and cardiac repair. Despite their utility, design guidelines for engineering …

Physical networks from entropy-driven non-covalent interactions

AC Yu, H Lian, X Kong, H Lopez Hernandez… - Nature …, 2021 - nature.com
Physical networks typically employ enthalpy-dominated crosslinking interactions that
become more dynamic at elevated temperatures, leading to network softening. Moreover …

Supramolecular reinforcement of polymer–nanoparticle hydrogels for modular materials design

G Bovone, EA Guzzi, S Bernhard, T Weber… - Advanced …, 2022 - Wiley Online Library
Moldable hydrogels are increasingly used as injectable or extrudable materials in
biomedical and industrial applications owing to their ability to flow under applied stress …

Supramolecular hydrogels: Mechanical strengthening with dynamics

Y Li, C Zhu, Y Dong, D Liu - Polymer, 2020 - Elsevier
Supramolecular hydrogels display unique dynamic features such as self-healing and
injectability which are endowed by their non-covalent crosslinking. These extraordinary …

Modular and photoreversible polymer–nanoparticle hydrogels via host–guest interactions

S Bernhard, L Ritter, M Müller, W Guo, EA Guzzi… - Small, 2024 - Wiley Online Library
Polymer–nanoparticle (PNP) hydrogels are a class of nanocomposite materials showing
potential as injectable platforms for biomedical applications. Their design is limited by …

Yield‐Stress and Creep Control Depot Formation and Persistence of Injectable Hydrogels Following Subcutaneous Administration

CK Jons, AK Grosskopf, J Baillet, J Yan… - Advanced Functional …, 2022 - Wiley Online Library
Hydrogels that can be injected into the body using standard needles or catheters enable a
minimally invasive strategy to prolong local delivery of therapeutic cargo. In particular …

Cellulose and derivatives serving as natural, versatile and biocompatible polymers in biomedical applications

R V. More, V Antanitta. S, R Khonde… - … Journal of Polymeric …, 2024 - Taylor & Francis
Cellulose is one of the world's most abounding polymers, which could be obtained through a
miscellany of natural resources, plant cell walls, certain types of bacteria, algae, tunicates …

[HTML][HTML] Injectable liposome-based supramolecular hydrogels for the programmable release of multiple protein drugs

S Correa, AK Grosskopf, JH Klich, HL Hernandez… - Matter, 2022 - cell.com
Directing biological functions is at the heart of next-generation biomedical initiatives in tissue
and immuno-engineering. However, the ambitious goal of engineering complex biological …