Synthetic biology: bottom-up assembly of molecular systems
The bottom-up assembly of biological and chemical components opens exciting
opportunities to engineer artificial vesicular systems for applications with previously unmet …
opportunities to engineer artificial vesicular systems for applications with previously unmet …
Microbial rhodopsins: the last two decades
Microbial rhodopsins are diverse photoreceptive proteins containing a retinal chromophore
and are found in all domains of cellular life and are even encoded in genomes of viruses …
and are found in all domains of cellular life and are even encoded in genomes of viruses …
Optogenetics at the presynapse
Optogenetic actuators enable highly precise spatiotemporal interrogation of biological
processes at levels ranging from the subcellular to cells, circuits and behaving organisms …
processes at levels ranging from the subcellular to cells, circuits and behaving organisms …
Infrared difference spectroscopy of proteins: from bands to bonds
VA Lorenz-Fonfria - Chemical reviews, 2020 - ACS Publications
Infrared difference spectroscopy probes vibrational changes of proteins upon their
perturbation. Compared with other spectroscopic methods, it stands out by its sensitivity to …
perturbation. Compared with other spectroscopic methods, it stands out by its sensitivity to …
A distinct abundant group of microbial rhodopsins discovered using functional metagenomics
Many organisms capture or sense sunlight using rhodopsin pigments,, which are integral
membrane proteins that bind retinal chromophores. Rhodopsins comprise two distinct …
membrane proteins that bind retinal chromophores. Rhodopsins comprise two distinct …
Femtosecond-to-millisecond structural changes in a light-driven sodium pump
Light-driven sodium pumps actively transport small cations across cellular membranes.
These pumps are used by microorganisms to convert light into membrane potential and …
These pumps are used by microorganisms to convert light into membrane potential and …
Illuminating the brain: advances and perspectives in optoelectronics for neural activity monitoring and modulation
Optogenetic modulation of brain neural activity that combines optical and electrical modes in
a unitary neural system has recently gained robust momentum. Controlling illumination …
a unitary neural system has recently gained robust momentum. Controlling illumination …
Rhodopsins at a glance
Rhodopsins are photoreceptive membrane proteins consisting of a common heptahelical
transmembrane architecture that contains a retinal chromophore. Rhodopsin was first …
transmembrane architecture that contains a retinal chromophore. Rhodopsin was first …
Rhodopsin-bestrophin fusion proteins from unicellular algae form gigantic pentameric ion channels
Many organisms sense light using rhodopsins, photoreceptive proteins containing a retinal
chromophore. Here we report the discovery, structure and biophysical characterization of …
chromophore. Here we report the discovery, structure and biophysical characterization of …
Optogenetics: background, methodological advances and potential applications for cardiovascular research and medicine
Optogenetics is an elegant approach of precisely controlling and monitoring the biological
functions of a cell, group of cells, tissues, or organs with high temporal and spatial resolution …
functions of a cell, group of cells, tissues, or organs with high temporal and spatial resolution …