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The intestine as an endocrine organ and the role of gut hormones in metabolic regulation
Gut hormones orchestrate pivotal physiological processes in multiple metabolically active
tissues, including the pancreas, liver, adipose tissue, gut and central nervous system …
tissues, including the pancreas, liver, adipose tissue, gut and central nervous system …
Future of theranostics: an outlook on precision oncology in nuclear medicine
T Langbein, WA Weber, M Eiber - Journal of Nuclear Medicine, 2019 - jnm.snmjournals.org
Molecular alterations in malignant disease result in the expression or upregulations of
various targets that can be used for imaging and treatment with radiopharmaceuticals. This …
various targets that can be used for imaging and treatment with radiopharmaceuticals. This …
A lamprey neural cell type atlas illuminates the origins of the vertebrate brain
The vertebrate brain emerged more than~ 500 million years ago in common evolutionary
ancestors. To systematically trace its cellular and molecular origins, we established a …
ancestors. To systematically trace its cellular and molecular origins, we established a …
Biological macromolecules-based nanoformulation in improving wound healing and bacterial biofilm-associated infection: A review
A chronic wound is a serious complication associated with diabetes mellitus and is difficult to
heal due to high glucose levels, oxidative stress, and biofilm-associated microbial infection …
heal due to high glucose levels, oxidative stress, and biofilm-associated microbial infection …
Activation of mast cells by neuropeptides: the role of pro-inflammatory and anti-inflammatory cytokines
Mast cells (MCs) are tissue cells that are derived from bone marrow stem cells that
contribute to allergic reactions, inflammatory diseases, innate and adaptive immunity …
contribute to allergic reactions, inflammatory diseases, innate and adaptive immunity …
Molecular and cellular mechanisms of excitotoxic neuronal death
Glutamate receptor-mediated excitatory neurotransmission plays a key role in neural
development, differentiation and synaptic plasticity. However, excessive stimulation of …
development, differentiation and synaptic plasticity. However, excessive stimulation of …
β-Arrestin-biased allosteric modulator of NTSR1 selectively attenuates addictive behaviors
Small molecule neurotensin receptor 1 (NTSR1) agonists have been pursued for more than
40 years as potential therapeutics for psychiatric disorders, including drug addiction. Clinical …
40 years as potential therapeutics for psychiatric disorders, including drug addiction. Clinical …
Role of central dopamine in pain and analgesia
PB Wood - Expert review of neurotherapeutics, 2008 - Taylor & Francis
Recent insights have demonstrated a central role for dopaminergic neurotransmission in
modulating pain perception and natural analgesia within supraspinal regions, including the …
modulating pain perception and natural analgesia within supraspinal regions, including the …
Inflammation and neuropeptides: the connection in diabetic wound healing
Abnormal wound healing is a major complication of both type 1 and type 2 diabetes, with
nonhealing foot ulcerations leading in the worst cases to lower-limb amputation. Wound …
nonhealing foot ulcerations leading in the worst cases to lower-limb amputation. Wound …
Neurotensin and neurotensin receptors in stress-related disorders: Pathophysiology & novel drug targets
Neurotensin (NT) is a 13-amino acid neuropeptide widely distributed in the CNS that has
been involved in the pathophysiology of many neural and psychiatric disorders. There are …
been involved in the pathophysiology of many neural and psychiatric disorders. There are …