Deep reinforcement learning in radiation therapy planning optimization: A comprehensive review

C Li, Y Guo, X Lin, X Feng, D Xu, R Yang - Physica Medica, 2024 - Elsevier
Purpose: The formulation and optimization of radiation therapy plans are complex and time-
consuming processes that heavily rely on the expertise of medical physicists. Consequently …

Comparison of atlas-based and deep learning methods for organs at risk delineation on head-and-neck CT images using an automated treatment planning system

M Costea, A Zlate, M Durand, T Baudier… - Radiotherapy and …, 2022 - Elsevier
Background and purpose To investigate the performance of head-and-neck (HN) organs-at-
risk (OAR) automatic segmentation (AS) using four atlas-based (ABAS) and two deep …

[HTML][HTML] Automated planning for prostate stereotactic body radiation therapy on the 1.5 T MR-Linac

S Naccarato, M Rigo, R Pellegrini, P Voet… - Advances in radiation …, 2022 - Elsevier
Purpose Adaptive stereotactic body radiation therapy (SBRT) for prostate cancer (PC) by the
1.5 T MR-linac currently requires online planning by an expert user. A fully automated and …

[HTML][HTML] Updating a clinical Knowledge-Based Planning prediction model for prostate radiotherapy

A Scaggion, M Fusella, S Cavinato, F Dusi… - Physica Medica, 2023 - Elsevier
Background and purpose Clinical knowledge-based planning (KBP) models dedicated to
prostate radiotherapy treatment may require periodical updates to remain relevant and to …

Fully automated volumetric modulated arc therapy technique for radiation therapy of locally advanced breast cancer

L Marrazzo, L Redapi, R Pellegrini, P Voet, I Meattini… - Radiation …, 2023 - Springer
Background This study aimed to evaluate an a-priori multicriteria plan optimization algorithm
(mCycle) for locally advanced breast cancer radiation therapy (RT) by comparing …

Comprehensive dosimetric and clinical evaluation of lexicographic optimization-based planning for cervical cancer

S Trivellato, P Caricato, R Pellegrini… - Frontiers in …, 2022 - frontiersin.org
Aim In this study, a not yet commercially available fully-automated lexicographic optimization
(LO) planning algorithm, called mCycle (Elekta AB, Stockholm, Sweden), was validated for …

Implementation and evaluation of an intelligent automatic treatment planning robot for prostate cancer stereotactic body radiation therapy

Y Gao, C Shen, X Jia, YK Park - Radiotherapy and Oncology, 2023 - Elsevier
Purpose We previously developed a virtual treatment planner (VTP), an artificial intelligence
robot, operating a treatment planning system (TPS). Using deep reinforcement learning …

Implementation of automatic plan optimization in Italy: Status and perspectives

S Pallotta, L Marrazzo, S Calusi, R Castriconi, C Fiorino… - Physica Medica, 2021 - Elsevier
Purpose To investigate and report on the diffusion and clinical use of automated
radiotherapy planning systems in Italy and to assess the perspectives of the community of …

Evaluation of different algorithms for automatic segmentation of head-and-neck lymph nodes on CT images

M Costea, A Zlate, AA Serre, S Racadot… - Radiotherapy and …, 2023 - Elsevier
Purpose To investigate the performance of 4 atlas-based (multi-ABAS) and 2 deep learning
(DL) solutions for head-and-neck (HN) elective nodes (CTVn) automatic segmentation (AS) …

[HTML][HTML] Lexicographic optimization-based planning for stereotactic radiosurgery of brain metastases

S Trivellato, P Caricato, R Pellegrini, MC Daniotti… - Radiotherapy and …, 2024 - Elsevier
Aim To validate a fully-automated lexicographic optimization-planning system (mCycle,
Elekta) for single-(SL) and multiple-(ML, up to 4 metastases) lesions in intracranial …