Early environments can have significant and lasting effects on brain, body, and behavior
across the lifecourse. Here, we address current research efforts to understand how …

Identifying early neurocognitive mechanisms that confer risk for mental health problems is
one important avenue as we seek to develop successful early interventions. Currently …

The human brain undergoes rapid development during the first years of life. Beginning in
utero, a wide array of biological, social, and environmental factors can have lasting impacts …

Objectives In light of the youth mental health crisis, as 1 in 5 children have a mental disorder
diagnosis by age 3, identification of transdiagnostic behavioral vulnerability prior to …

Objectives Heightened irritability in adolescence is an impairing symptom that can lead to
negative outcomes in adulthood, but effective screening tools are lacking. This study aimed …

The field of adult neuroimaging relies on well-established principles in research design,
imaging sequences, processing pipelines, as well as safety and data collection protocols …

Abstract The HEALthy Brain and Child Development (HBCD) Study, a multi-site prospective
longitudinal cohort study, will examine human brain, cognitive, behavioral, social, and …

The integration of neurodevelopmental perspectives into clinical science has identified
irritability as an early dimensional marker of lifespan mental health risk. Elucidating the …

Endoscopy is vital for detecting and diagnosing gastrointestinal diseases. Systematic
examination protocols are key to enhancing detection, particularly for the early identification …

Objectives Characterizing the scope and import of early childhood irritability is essential for
real‐world actualization of this reliable indicator of transdiagnostic mental health risk. Thus …