[HTML][HTML] Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes

M Deponte - Biochimica et Biophysica Acta (BBA)-General Subjects, 2013 - Elsevier
BACKGROUND: Glutathione-dependent catalysis is a metabolic adaptation to chemical
challenges encountered by all life forms. In the course of evolution, nature optimized …

The Response to Heat Shock and Oxidative Stress in Saccharomyces cerevisiae

KA Morano, CM Grant, WS Moye-Rowley - Genetics, 2012 - academic.oup.com
A common need for microbial cells is the ability to respond to potentially toxic environmental
insults. Here we review the progress in understanding the response of the yeast …

Thioredoxin and related molecules–from biology to health and disease

CH Lillig, A Holmgren - Antioxidants & redox signaling, 2007 - liebertpub.com
Thioredoxin and glutaredoxin systems in mammalian cells utilize thiol and selenol groups to
maintain a reducing intracellular redox state acting as antioxidants and reducing agents in …

Oxidative stress in malaria parasite-infected erythrocytes: host–parasite interactions

K Becker, L Tilley, JL Vennerstrom, D Roberts… - International journal for …, 2004 - Elsevier
Experimenta naturae, like the glucose-6-phosphate dehydrogenase deficiency, indicate that
malaria parasites are highly susceptible to alterations in the redox equilibrium. This offers a …

Glutaredoxins: glutathione-dependent redox enzymes with functions far beyond a simple thioredoxin backup system

AP Fernandes, A Holmgren - Antioxidants and Redox Signaling, 2004 - liebertpub.com
Most cells contain high levels of glutathione and multiple glutaredoxins, which utilize the
reducing power of glutathione to catalyze disulfide reductions in the presence of NADPH …

Glutaredoxin systems

CH Lillig, C Berndt, A Holmgren - Biochimica et Biophysica Acta (BBA) …, 2008 - Elsevier
Glutaredoxins utilize the reducing power of glutathione to maintain and regulate the cellular
redox state and redox-dependent signaling pathways, for instance, by catalyzing reversible …

[HTML][HTML] The role of mitochondria in cellular iron–sulfur protein biogenesis and iron metabolism

R Lill, B Hoffmann, S Molik, AJ Pierik… - … et Biophysica Acta (BBA …, 2012 - Elsevier
Mitochondria play a key role in iron metabolism in that they synthesize heme, assemble iron–
sulfur (Fe/S) proteins, and participate in cellular iron regulation. Here, we review the latter …

Roles of the Glutathione- and Thioredoxin-Dependent Reduction Systems in the Escherichia Coli and Saccharomyces Cerevisiae Responses to Oxidative Stress

O Carmel-Harel, G Storz - Annual Reviews in Microbiology, 2000 - annualreviews.org
▪ Abstract The glutathione-and thioredoxin-dependent reduction systems are responsible for
maintaining the reduced environment of the Escherichia coli and Saccharomyces cerevisiae …

Stress-controlled transcription factors, stress-induced genes and stress tolerance in budding yeast

F Estruch - FEMS microbiology reviews, 2000 - academic.oup.com
The transcriptional response to environmental changes is a major topic in both basic and
applied research. From a basic point of view, to understand this response includes …

Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress

M Ralser, MM Wamelink, A Kowald, B Gerisch… - Journal of biology, 2007 - Springer
Background Eukaryotic cells have evolved various response mechanisms to counteract the
deleterious consequences of oxidative stress. Among these processes, metabolic alterations …