The use of genomics in medicine is expanding rapidly, but information systems are lagging
in their ability to support genomic workflows both from the laboratory and patient-facing …

Two major goals of the Electronic Medical Record and Genomics (eMERGE) Network are to
learn how best to return research results to patient/participants and the clinicians who care …

Importance Knowledge about the spectrum of diseases associated with hereditary cancer
syndromes may improve disease diagnosis and management for patients and help to …

Background Population-based genomic screening has the predicted ability to reduce
morbidity and mortality associated with medically actionable conditions. However, much …

Summary The Healthy Oregon Project (HOP) is a statewide effort that aims to build a large
research repository and influence the health of Oregonians through providing no-cost …

Genetic testing is recommended as part of an autism assessment, and most parents support
genetic testing for their minor children. However, the impact on parents of receiving a …

Abstract Purpose The goal of Electronic Medical Records and Genomics (eMERGE) Phase
III Network was to return actionable sequence variants to 25,084 consenting participants …

Background Unbiased estimates of penetrance are challenging but critically important to
make informed choices about strategies for risk management through increased …

Latin Americans are underrepresented in genetic studies, increasing disparities in
personalized genomic medicine. Despite available genetic data from thousands of Latin …

The public health impact of genomic screening can be enhanced by cascade testing.
However, cascade testing depends on communication of results to family members. While …