Enhancing the stability of antimicrobial peptides: From design strategies to biomedical applications

S Xu, P Tan, Q Tang, T Wang, Y Ding, H Fu… - Chemical Engineering …, 2023 - Elsevier
Antimicrobial peptides (AMPs) offer unique advantages due to their membrane-active
antimicrobial mechanisms, which reduce the likelihood of resistance development …

Molecularly targeted fluorescent sensors for visualizing and tracking cellular senescence

Z He, K Xu, Y Li, H Gao, T Miao, R Zhao, Y Huang - Biosensors, 2023 - mdpi.com
Specific identification and monitoring of senescent cells are essential for the in-depth
understanding and regulation of senescence-related life processes and diseases …

pH‐triggered size‐transformable and bioactivity‐switchable self‐assembling chimeric peptide nanoassemblies for combating drug‐resistant bacteria and biofilms

P Tan, C Wu, Q Tang, T Wang, C Zhou… - Advanced …, 2023 - Wiley Online Library
Drug‐resistant bacteria and biofilm‐associated infections are prominent problems in the
field of antibacterial medicine, seriously affecting human and animal health. Despite the …

Dietary D-xylose promotes intestinal health by inducing phage production in Escherichia coli

J Hu, Y Wu, L Kang, Y Liu, H Ye, R Wang… - npj Biofilms and …, 2023 - nature.com
Elimination of specific enteropathogenic microorganisms is critical to gut health. However,
the complexity of the gut community makes it challenging to target specific bacterial …

Design of high-selectivity co-assembled peptide nanofibers against bacterial infection in piglets

S Xu, P Tan, Q Tang, T Wang, Y Ding… - … Applied Materials & …, 2023 - ACS Publications
Antibiotic resistance is an escalating global health concern that could result in tens of
millions of deaths annually from drug-resistant bacterial infections in the future, especially in …

[HTML][HTML] An Overview of Stimuli-Responsive Intelligent Antibacterial Nanomaterials

J Zhang, W Tang, X Zhang, Z Song, T Tong - Pharmaceutics, 2023 - mdpi.com
Drug-resistant bacteria and infectious diseases associated with biofilms pose a significant
global health threat. The integration and advancement of nanotechnology in antibacterial …

Engineered peptides harboring cation motifs against multidrug-resistant bacteria

L Shang, C Chen, R Sun, J Guo, J Liu… - … Applied Materials & …, 2024 - ACS Publications
Multidrug-resistant (MDR) pathogens pose a serious threat to the health and life of humans,
necessitating the development of new antimicrobial agents. Herein, we develop and …

Optimized charge/hydrophobicity balance of antimicrobial peptides against polymicrobial abdominal infections

K Du, ZR Yang, H Qin, T Ma, J Tang… - Macromolecular …, 2024 - Wiley Online Library
Antimicrobial peptides (AMPs) potentially serve as ideal antimicrobial agents for the
treatment of polymicrobial abdominal infections due to their broad‐spectrum antimicrobial …

Glucose and pH dual-responsive hydrogels with antibacterial, reactive oxygen species scavenging, and angiogenesis properties for promoting the healing of infected …

Z Li, L Chen, S Yang, J Han, Y Zheng, Z Chen, X Shi… - Acta Biomaterialia, 2024 - Elsevier
The healing process of diabetic foot ulcers is challenging due to the presence of a complex
and severe inflammatory microenvironment, characterized by hyperglycemia, low pH …

Phage‐displayed heptapeptide sequence conjugation significantly improves the specific targeting ability of antimicrobial peptides against Staphylococcus aureus

T Wang, P Tan, Q Tang, C Zhou, Y Ding, S Xu, M Song… - mLife, 2024 - Wiley Online Library
Broad‐spectrum antibacterial drugs often lack specificity, leading to indiscriminate
bactericidal activity, which can disrupt the normal microbial balance of the host flora and …