Cancer causes considerable morbidity and mortality across the world. Socioeconomic,
environmental, and lifestyle factors contribute to the increasing cancer prevalence …

Over the last two decades, since the initial discovery of human papillomavirus (HPV) type 16
and 18 DNAs in cervical cancers by Dr. Harald zur Hausen (winner of the Nobel Prize in …

Because Notch signaling is implicated in colon cancer tumorigenesis and protects cells from
apoptosis by inducing prosurvival targets, it was hypothesized that inhibition of Notch …

Cancer development results from deregulated control of stem cell populations and
alterations in their surrounding environment. Notch signaling is an important form of direct …

Understanding the complexity of cancer depends on an elucidation of the underlying
regulatory networks, at the cellular and intercellular levels and in their temporal dimension …

The ubiquitin-specific protease 7 (USP7)-murine double minute 2 (MDM2)-p53 network
plays an important role in the regulation of p53, a tumor suppressor which plays critical roles …

Recurrent epidemics of influenza are due to the frequent emergence of antigenic variants.
With co-circulation of two influenza A subtypes and two antigenically distinct lineages of B …

The Notch family of transmembrane receptors are important mediators of cell fate
determination. Accordingly, Notch signaling is intimately involved in the development of …

The aims of this study were to determine potency of oxaliplatin in combination with curcumin
in oxaliplatin‐resistant cell lines in vitro and to evaluate the efficacy of a novel curcumin …

The notch signalling pathway is involved in differentiation, proliferation, angiogenesis,
vascular remodelling, and apoptosis. Deregulated expression of notch receptors, ligands …