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Sleep function: Toward elucidating an enigma
Sleep function remains controversial. Individual perspectives frame the issue of sleep
function differently. We briefly illustrate how sleep measurement and the evolution, tissue …
function differently. We briefly illustrate how sleep measurement and the evolution, tissue …
Aging and Alzheimer's disease: comparison and associations from molecular to system level
Alzheimer's disease is the most prevalent cause of dementia, which is defined by the
combined presence of amyloid and tau, but researchers are gradually moving away from the …
combined presence of amyloid and tau, but researchers are gradually moving away from the …
Sleep: a novel mechanistic pathway, biomarker, and treatment target in the pathology of Alzheimer's disease?
Sleep disruption appears to be a core component of Alzheimer's disease (AD) and its
pathophysiology. Signature abnormalities of sleep emerge before clinical onset of AD …
pathophysiology. Signature abnormalities of sleep emerge before clinical onset of AD …
Is serotonin an upper or a downer? The evolution of the serotonergic system and its role in depression and the antidepressant response
The role of serotonin in depression and antidepressant treatment remains unresolved
despite decades of research. In this paper, we make three major claims. First, serotonin …
despite decades of research. In this paper, we make three major claims. First, serotonin …
[HTML][HTML] Sleep loss: a novel risk factor for insulin resistance and Type 2 diabetes
Chronic sleep loss as a consequence of voluntary bedtime restriction is an endemic
condition in modern society. Although sleep exerts marked modulatory effects on glucose …
condition in modern society. Although sleep exerts marked modulatory effects on glucose …
Neural basis of alertness and cognitive performance impairments during sleepiness. I. Effects of 24 h of sleep deprivation on waking human regional brain activity
The negative effects of sleep deprivation on alertness and cognitive performance suggest
decreases in brain activity and function, primarily in the thalamus, a subcortical structure …
decreases in brain activity and function, primarily in the thalamus, a subcortical structure …
Functional neuroanatomy of human rapid-eye-movement sleep and dreaming
P Maquet, JM Péters, J Aerts, G Delfiore, C Degueldre… - Nature, 1996 - nature.com
Abstract RAPID-EYE-MOVEMENT (REM) sleep is associated with intense neuronal activity,
ocular saccades, muscular atonia and dreaming1, 2. The function of REM sleep remains …
ocular saccades, muscular atonia and dreaming1, 2. The function of REM sleep remains …
Dreaming and the brain: toward a cognitive neuroscience of conscious states
Sleep researchers in different disciplines disagree about how fully dreaming can be
explained in terms of brain physiology. Debate has focused on whether REM sleep …
explained in terms of brain physiology. Debate has focused on whether REM sleep …
Brain function in coma, vegetative state, and related disorders
We review the nosological criteria and functional neuroanatomical basis for brain death,
coma, vegetative state, minimally conscious state, and the locked-in state. Functional …
coma, vegetative state, minimally conscious state, and the locked-in state. Functional …
The reinterpretation of dreams: An evolutionary hypothesis of the function of dreaming
Several theories claim that dreaming is a random by-product of REM sleep physiology and
that it does not serve any natural function. Phenomenal dream content, however, is not as …
that it does not serve any natural function. Phenomenal dream content, however, is not as …