Antimicrobial resistance is an old and silent pandemic. Resistant organisms emerge in
parallel with new antibiotics, leading to a major global public health crisis over time …

Bacterial drug resistance has become a global public health threat, among which the
infection of carbapenem-resistant Enterobacterales (CRE) is one of the top noticeable …

Multidrug efflux pumps function at the frontline to protect bacteria against antimicrobials by
decreasing the intracellular concentration of drugs. This protective barrier consists of a …

Although hypervirulent Klebsiella pneumoniae (hvKP) can produce community-acquired
infections that are fatal in young and adult hosts, such as pyogenic liver abscess …

Antimicrobial resistance (AMR) poses a serious global health concern, resulting in a
significant number of deaths annually due to infections that are resistant to treatment. Amidst …

Efflux is a natural process found in all prokaryotic and eukaryotic cells that removes a
diverse range of substrates from inside to outside. Many antibiotics are substrates of …

Significant developments in the understanding and manipulation of microbial metabolism
have enabled the use of engineered biological systems toward a more sustainable energy …

Abstract Resistance-Nodulation-Division (RND) efflux pumps are responsible for multidrug
resistance in Pseudomonas aeruginosa. The present study aimed to evaluate the …

Antimicrobial resistance is one of the greatest dangers to public health of the 21st century,
threatening the treatment and prevention of infectious diseases globally. Disinfection, the …

The rapid increase in pathogenic microorganisms with antimicrobial resistant profiles has
become a significant public health problem globally. The management of this issue using …