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Cell-extracellular matrix interactions in normal and diseased skin
FM Watt, H Fujiwara - Cold Spring Harbor Perspectives …, 2011 - cshperspectives.cshlp.org
Mammalian skin comprises a multi-layered epithelium, the epidermis, and an underlying
connective tissue, the dermis. The epidermal extracellular matrix is a basement membrane …
connective tissue, the dermis. The epidermal extracellular matrix is a basement membrane …
Aging in the sebaceous gland
X Hou, Z Wei, CC Zouboulis, Q Ju - Frontiers in Cell and …, 2022 - frontiersin.org
Sebaceous glands (SGs) originate from hair follicular stem cells and secrete lipids to
lubricate the skin. The coordinated effects of intrinsic and extrinsic aging factors generate …
lubricate the skin. The coordinated effects of intrinsic and extrinsic aging factors generate …
Oncogenic KRAS-driven metabolic reprogramming in pancreatic cancer cells utilizes cytokines from the tumor microenvironment
A hallmark of pancreatic ductal adenocarcinoma (PDAC) is an exuberant stroma comprised
of diverse cell types that enable or suppress tumor progression. Here, we explored the role …
of diverse cell types that enable or suppress tumor progression. Here, we explored the role …
Cell-type independent MYC target genes reveal a primordial signature involved in biomass accumulation
The functions of key oncogenic transcription factors independent of context have not been
fully delineated despite our richer understanding of the genetic alterations in human …
fully delineated despite our richer understanding of the genetic alterations in human …
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Pancreatic ductal adenocarcinoma (PDAC) is still one of the deadliest cancers in oncology
because of its increasing incidence and poor survival rate. More than 90% of PDAC patients …
because of its increasing incidence and poor survival rate. More than 90% of PDAC patients …
Myc-dependent dedifferentiation of Gata6+ epidermal cells resembles reversal of terminal differentiation
Dedifferentiation is the process by which terminally differentiated cells acquire the properties
of stem cells. During mouse skin wound healing, the differentiated Gata6-lineage positive …
of stem cells. During mouse skin wound healing, the differentiated Gata6-lineage positive …
miR-24 triggers epidermal differentiation by controlling actin adhesion and cell migration
I Amelio, AM Lena, G Viticchiè… - Journal of Cell …, 2012 - rupress.org
During keratinocyte differentiation and stratification, cells undergo extensive remodeling of
their actin cytoskeleton, which is important to control cell mobility and to coordinate and …
their actin cytoskeleton, which is important to control cell mobility and to coordinate and …