Plant-derived immunomodulators: an insight on their preclinical evaluation and clinical trials

I Jantan, W Ahmad, SNA Bukhari - Frontiers in plant science, 2015 - frontiersin.org
The phagocyte–microbe interactions in the immune system is a defense mechanism but
when excessively or inappropriately deployed can harm host tissues and participate in the …

Multifaceted roles of PGE2 in inflammation and cancer

M Nakanishi, DW Rosenberg - Seminars in immunopathology, 2013 - Springer
Abstract Prostaglandin E 2 (PGE 2) is a bioactive lipid that elicits a wide range of biological
effects associated with inflammation and cancer. PGE 2 exerts diverse effects on cell …

Clinical pharmacology of non-steroidal anti-inflammatory drugs: a review

S Bacchi, P Palumbo, A Sponta… - Anti-Inflammatory & …, 2012 - ingentaconnect.com
Non-steroidal anti-inflammatory drugs (NSAIDs) are a group of often chemically unrelated
compounds with some common therapeutic actions and side effects. They have potent anti …

Review of Pharmacological Effects of Myrtus communis L. and its Active Constituents

G Alipour, S Dashti, H Hosseinzadeh - Phytotherapy research, 2014 - Wiley Online Library
Myrtle (Myrtus communis L., Myrtaceae) is a medicinal herb used worldwide in traditional
medicine. A large number of components have been isolated from this herb. Polyphenols …

Toward develo** chemical modulators of Hsp60 as potential therapeutics

Q Meng, BX Li, X **ao - Frontiers in molecular biosciences, 2018 - frontiersin.org
The 60 kDa heat shock protein (Hsp60) is classically known as a mitochondrial chaperonin
protein working together with co-chaperonin 10 kDa heat shock protein (Hsp10). This …

Anti-inflammatory and cytoprotective effects of selected Pakistani medicinal plants in Helicobacter pylori-infected gastric epithelial cells

SF Zaidi, JS Muhammad, S Shahryar… - Journal of …, 2012 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Helicobacter pylori infection is associated with
gastritis, peptic ulcer, and gastric cancer. Due to its high global prevalence and uprising …

Perspective of microsomal prostaglandin E2 synthase-1 as drug target in inflammation-related disorders

A Koeberle, O Werz - Biochemical pharmacology, 2015 - Elsevier
Prostaglandin (PG) E 2 encompasses crucial roles in pain, fever, inflammation and diseases
with inflammatory component, such as cancer, but is also essential for gastric, renal …

Nonsteroidal anti‐inflammatory therapy: a journey toward safety

C Pereira‐Leite, C Nunes, SK Jamal… - Medicinal research …, 2017 - Wiley Online Library
The efficacy of nonsteroidal anti‐inflammatory drugs (NSAIDs) against inflammation, pain,
and fever has been supporting their worldwide use in the treatment of painful conditions and …

The therapeutic value of Myrtus communis L.: an updated review

AE Al-Snafi, JO Teibo, HM Shaheen, OA Akinfe… - Naunyn-Schmiedeberg's …, 2024 - Springer
Abstract Myrtus communis L.(Family: Myrtaceae) is naturally found in the western part of
Asia, Southern Europe, and North Africa. It has been reportedly applied in pharmaceutical …

Antioxidant Activity of Myrtus communis L. and Myrtus nivellei Batt. & Trab. Extracts: A Brief Review

A Hennia, MG Miguel, S Nemmiche - Medicines, 2018 - mdpi.com
Myrtus communis L.(myrtle) and Myrtus nivellei Batt. & Trab.(Saharan myrtle) have been
used in folk medicine for alleviating some ailments. M. communis is largely distributed in the …