▪ Abstract Neurotransmitter release is mediated by exocytosis of synaptic vesicles at the
presynaptic active zone of nerve terminals. To support rapid and repeated rounds of release …

Conclusions The results reviewed suggest that membrane fusion in diverse biological fusion
reactions involves formation of some specific intermediates: stalks and pores. Energy of …

SPONTANEOUS errors in DNA replication have been suggested to play a significant role in
neoplastic transformation and to explain the chromosomal alterations seen in cancer cells1 …

In mast cells and granulocytes, exocytosis starts with the formation of a fusion pore,,. It has
been suggested that neurotransmitters may be released through such a narrow pore without …

PATCH-CLAMP experiments have shown that fusion of secretory granules with the plasma
membrane does not always occur as an all-or-none event, but can develop slowly in a …

Common themes are emerging from the study of viral, cell-cell, intracellular, and liposome
fusion. Viral and cellular membrane fusion events are mediated by fusion proteins or fusion …

Most intracellular pathogens avoid lysing their host cells during invasion by wrap**
themselves in a vacuolar membrane. This parasitophorous vacuole membrane (PVM) is …

Exocytosis, the fusion of secretory vesicles with the plasma membrane to allow release of
the contents of the vesicles into the extracellular environment, and endocytosis, the …

Exocytosis, or the fusion of cytoplasmic vesicles with the cell membrane, occurs in nearly all
eukaryotic cells, but its mechanism is not understood. Morphological1, 2 and …

The mechanism of bilayer unification in biological fusion is unclear. We reversibly arrested
hemagglutinin (HA)-mediated cell–cell fusion right before fusion pore opening. A low-pH …