Diagnosis and treatment of pulmonary arterial hypertension: a review

NF Ruopp, BA Cockrill - Jama, 2022 - jamanetwork.com
Importance Pulmonary arterial hypertension (PAH) is a subtype of pulmonary hypertension
(PH), characterized by pulmonary arterial remodeling. The prevalence of PAH is …

Obesity, estrogens and adipose tissue dysfunction–implications for pulmonary arterial hypertension

KM Mair, R Gaw, MR MacLean - Pulmonary circulation, 2020 - journals.sagepub.com
Obesity is a prevalent global public health issue characterized by excess body fat. Adipose
tissue is now recognized as an important endocrine organ releasing an abundance of …

Mechanisms of immunity in acutely decompensated cirrhosis and acute‐on‐chronic liver failure

C Engelmann, IW Zhang, J Clària - Liver International, 2023 - Wiley Online Library
The identification of systemic inflammation (SI) as a central player in the orchestration of
acute‐on‐chronic liver failure (ACLF) has opened new avenues for the understanding of the …

Portopulmonary hypertension: from bench to bedside

C Thomas, V Glinskii, V de Jesus Perez… - Frontiers in Medicine, 2020 - frontiersin.org
Portopulmonary hypertension (PoPH) is defined as pulmonary arterial hypertension (PAH)
associated with portal hypertension and is a subset of Group 1 pulmonary hypertension …

Pulmonary arterial hypertension: sex matters

JP Dignam, S Sharma, I Stasinopoulos… - British Journal of …, 2024 - Wiley Online Library
Pulmonary arterial hypertension (PAH) is a complex disease of multifactorial origin. While
registries have demonstrated that women are more susceptible to the disease, females with …

Human liver single nuclear RNA sequencing implicates BMPR2, GDF15, arginine, and estrogen in portopulmonary hypertension

A Jose, JM Elwing, SM Kawut, MW Pauciulo… - Communications …, 2023 - nature.com
Portopulmonary hypertension (PoPH) is a type of pulmonary vascular disease due to portal
hypertension that exhibits high morbidity and mortality. The mechanisms driving disease are …

Sex and gender in pulmonary arterial hypertension

C Cheron, SA McBride, F Antigny… - European …, 2021 - Eur Respiratory Soc
Pulmonary arterial hypertension (PAH) is a rare disease characterised by pulmonary
vascular remodelling and elevated pulmonary pressure, which eventually leads to right …

Clinical implications and management of spontaneous portosystemic shunts in liver cirrhosis

S Juncu, H Minea, I Girleanu, L Huiban, C Muzica… - Diagnostics, 2024 - mdpi.com
Portal hypertension from chronic liver disease leads to the formation of collateral blood
vessels called spontaneous portosystemic shunts (SPSS). These shunts may form from …

Portopulmonary hypertension: management and liver transplantation evaluation

HM DuBrock - Chest, 2023 - Elsevier
Portopulmonary hypertension (POPH) affects 5% to 6% of patients with advanced liver
disease and accounts for 5% to 15% of pulmonary arterial hypertension (PAH) cases …

Prevalence and associated factors of portopulmonary hypertension in patients with portal hypertension: a case‐control study

Y Shao, X Yin, T Qin, R Zhang… - BioMed Research …, 2021 - Wiley Online Library
Background and Aims. There are few studies on the prevalence and clinical characteristics
of portopulmonary hypertension (POPH) in patients with portal hypertension. In addition …