Squeezing for life–properties of red blood cell deformability

R Huisjes, A Bogdanova, WW Van Solinge… - Frontiers in …, 2018 - frontiersin.org
Deformability is an essential feature of blood cells (RBCs) that enables them to travel
through even the smallest capillaries of the human body. Deformability is a function of (i) …

Circulating extracellular vesicles in healthy and pathological pregnancies: A sco** review of methodology, rigour and results

MVC Barnes, P Pantazi, B Holder - Journal of Extracellular …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) play a crucial role in pregnancy, revealed by the presence of
placental‐derived EVs in maternal blood, their in vitro functionality, and their altered cargo in …

Tetraspanins distinguish separate extracellular vesicle subpopulations in human serum and plasma–Contributions of platelet extracellular vesicles in plasma samples

N Karimi, R Dalirfardouei, T Dias… - Journal of …, 2022 - Wiley Online Library
Background: The ability to isolate extracellular vesicles (EVs) from blood is vital in the
development of EVs as disease biomarkers. Both serum and plasma can be used, but few …

Glutaraldehyde–a subtle tool in the investigation of healthy and pathologic red blood cells

A Abay, G Simionato, R Chachanidze… - Frontiers in …, 2019 - frontiersin.org
Glutaraldehyde is a well-known substance used in biomedical research to fix cells. Since
hemolytic anemias are often associated with red blood cell shape changes deviating from …

Red Blood Cell Passage of Small Capillaries Is Associated with Transient Ca2+-mediated Adaptations

JG Danielczok, E Terriac, L Hertz… - Frontiers in …, 2017 - frontiersin.org
When red blood cells (RBCs) pass constrictions or small capillaries they need to pass
apertures falling well below their own cross section size. We used different means of …

Heterogeneity of red blood cells: causes and consequences

A Bogdanova, L Kaestner, G Simionato… - Frontiers in …, 2020 - frontiersin.org
Mean values of hematological parameters are currently used in the clinical laboratory
settings to characterize red blood cell properties. Those include red blood cell indices …

'Gardos Channelopathy': a variant of hereditary Stomatocytosis with complex molecular regulation

E Fermo, A Bogdanova, P Petkova-Kirova… - Scientific reports, 2017 - nature.com
The Gardos channel is a Ca2+ sensitive, K+ selective channel present in several tissues
including RBCs, where it is involved in cell volume regulation. Recently, mutations at two …

ROS formation, mitochondrial potential and osmotic stability of the lamprey red blood cells: effect of adrenergic stimulation and hypoosmotic stress

ES Chelebieva, ES Kladchenko, IV Mindukshev… - Fish Physiology and …, 2024 - Springer
Semi-anadromous animals experience salinity fluctuations during their life-span period.
Alterations of environmental conditions induce stress response where catecholamines (CA) …

RedTell: an AI tool for interpretable analysis of red blood cell morphology

A Sadafi, M Bordukova, A Makhro, N Navab… - Frontiers in …, 2023 - frontiersin.org
Introduction: Hematologists analyze microscopic images of red blood cells to study their
morphology and functionality, detect disorders and search for drugs. However, accurate …

The function of ion channels and membrane potential in red blood cells: toward a systematic analysis of the erythroid channelome

M von Lindern, S Egée, P Bianchi… - Frontiers in Physiology, 2022 - frontiersin.org
Erythrocytes represent at least 60% of all cells in the human body. During circulation, they
experience a huge variety of physical and chemical stimulations, such as pressure, shear …