Immunopathogenesis of genital Chlamydia infection: insights from mouse models

J Dockterman, J Coers - Pathogens and Disease, 2021 - academic.oup.com
Chlamydiae are pathogenic intracellular bacteria that cause a wide variety of diseases
throughout the globe, affecting the eye, lung, coronary arteries and female genital tract …

The mucosal immune response to Chlamydia trachomatis infection of the reproductive tract in women

T Agrawal, V Vats, S Salhan, A Mittal - Journal of reproductive immunology, 2009 - Elsevier
Sexually transmitted Chlamydia trachomatis infection is an important public health concern
with major adverse effects on female reproductive tract health and function. The magnitude …

Cervical Cytokines Associated With Chlamydia trachomatis Susceptibility and Protection

TB Poston, DAE Lee, T Darville, W Zhong… - The Journal of …, 2019 - academic.oup.com
Background Chlamydia trachomatis can cause reproductive morbidities after ascending to
the upper genital tract of women, and repeated infection can lead to worse disease. Data …

Modeling the Impact of Potential Vaccines on Epidemics of Sexually Transmitted Chlamydia trachomatis Infection

RT Gray, KW Beagley, P Timms… - The Journal of infectious …, 2009 - academic.oup.com
Background We investigated the likely impact of vaccines on the prevalence of and
morbidity due to Chlamydia trachomatis (chlamydia) infections in heterosexual populations …

Immunotherapy of patients with recurrent spontaneous miscarriage and idiopathic infertility: does the immunization-dependent Th2 cytokine overbalance really matter …

JR Wilczyński, P Radwan, H Tchórzewski… - Archivum immunologiae …, 2012 - Springer
Recurrent spontaneous miscarriage (RSM) and idiopathic infertility (IIF) are partially caused
by immunologic disturbances. Paternal lymphocyte immunization (PLI) is proposed for …

An atypical CD8 T‐cell response to Chlamydia muridarum genital tract infections includes T cells that produce interleukin‐13

RM Johnson, MS Kerr, JE Slaven - Immunology, 2014 - Wiley Online Library
Chlamydia trachomatis urogenital serovars D–K are intracellular bacterial pathogens that
replicate almost exclusively in human reproductive tract epithelium. In the C. muridarum …

Immunopathogenesis in Chlamydia trachomatis Infected Women

MT Mascellino, P Boccia, A Oliva - … Scholarly Research Notices, 2011 - Wiley Online Library
We examine the Chlamydia trachomatis (Ct) immunopathogenesis on the basis of the
complex interaction between host immune response and virulence microorganism factors …

The basis and value of currently used immunomodulatory therapies in recurrent miscarriage

AS Bansal, B Bajardeen, MY Thum - Journal of reproductive immunology, 2012 - Elsevier
Recurrent miscarriage (RM) without an obvious identifiable cause may arise from excessive
maternal T and natural killer (NK) cell activity against the trophoblast or early embryo …

Association of genital Chlamydia trachomatis infection with female infer-tility, study in a Tertiary Care Hospital in Eastern India

M Ghosh, S Choudhuri, RG Ray… - The open …, 2015 - pmc.ncbi.nlm.nih.gov
Background: Chlamydia trachomatis is recognized as one of the most common sexually
transmitted pathogen in the world. 50-80% of infected females are asymptomatic. These …

Association of MICA gene polymorphisms with Chlamydia trachomatis infection and related tubal pathology in infertile women

B Mei, Q Luo, K Du, Z Huo, F Wang… - Human Reproduction, 2009 - academic.oup.com
BACKGROUND The course and morbidity of Chlamydia trachomatis infections are
determined by host genetic factors, virulence of the micro-organism and environmental …