The emerging picture of taste coding at the periphery is one of elegant simplicity. Contrary to
what was generally believed, it is now clear that distinct cell types expressing unique …

G protein-coupled receptors (GPCRs) are the largest family of membrane-bound receptors
and also the targets of many drugs. Understanding of the functional significance of the wide …

Humans perceive thousands of compounds as bitter. In sharp contrast, only∼ 25 taste 2
receptors (TAS2R) bitter taste receptors have been identified, raising the question as to how …

Five canonical tastes, bitter, sweet, umami (amino acid), salty, and sour (acid), are detected
by animals as diverse as fruit flies and humans, consistent with a near-universal drive to …

Chemosensory receptors are essential for the survival of organisms that range from bacteria
to mammals. Recent studies have shown that the numbers of functional chemosensory …

One key to animal survival is the detection and avoidance of potentially harmful compounds
by their bitter taste. Variable numbers of taste 2 receptor genes expressed in the gustatory …

Mammalian sweet taste is primarily mediated by the type 1 taste receptor Tas1r2/Tas1r3,
whereas Tas1r1/Tas1r3 act as the principal umami taste receptor. Bitter taste is mediated by …

Birds are renowned for their exceptional vision and the way that this enables them to survive
and navigate the world in such a unique way. However, it is now recognised that avian …

Taste receptors function as one of the interfaces between internal and external milieus.
Taste receptors for sweet and umami (T1R [taste receptor, type 1]), bitter (T2R [taste …

Sensory systems define an animal's capacity for perception and can evolve to promote
survival in new environmental niches. We have uncovered a noncanonical mechanism for …