ECM microenvironment in vascular homeostasis: new targets for atherosclerosis
L Zhang, Q Feng, W Kong - Physiology, 2024 - journals.physiology.org
Alterations in vascular extracellular matrix (ECM) components, interactions, and mechanical
properties influence both the formation and stability of atherosclerotic plaques. This review …
properties influence both the formation and stability of atherosclerotic plaques. This review …
Contribution of the arterial cells to atherosclerosis and plaque formation
T Naiya, I Meganathan, N Ness… - American Journal …, 2024 - journals.physiology.org
Atherosclerosis is commonly known as an inflammatory disease that is characterized by lipid
deposition in the arterial wall, causing gradual restriction or complete blockade of blood …
deposition in the arterial wall, causing gradual restriction or complete blockade of blood …
Plasma proteomics and lipidomics facilitate elucidation of the link between Alzheimer's disease development and vessel wall fragility
SM Tokuoka, F Hamano, A Kobayashi, S Adachi… - Scientific Reports, 2024 - nature.com
Abstract Proximity Extension Assay (PEA) and mass spectrometry (MS) methodologies were
utilized for the proteomic and lipidomic characterization of plasma specimens from patients …
utilized for the proteomic and lipidomic characterization of plasma specimens from patients …
Circulating biomarkers of cardiovascular disease are related to aneurysm volume in abdominal aortic aneurysm
E Bouwens, A Vanmaele, SE Hoeks… - Vascular …, 2023 - journals.sagepub.com
Background: Surveillance programs in abdominal aortic aneurysms (AAA) are mainly based
on imaging and leave room for improvement to timely identify patients at risk for AAA growth …
on imaging and leave room for improvement to timely identify patients at risk for AAA growth …
Implications of Sm22α-Cre expression in keratinocytes and unanticipated inflammatory skin lesion in a model of atherosclerosis
Genetically modified mice are widely used to recapitulate human diseases. Atherosclerosis
can be induced in mice with low-density lipoprotein receptor (Ldlr)-deficiency and a high-fat …
can be induced in mice with low-density lipoprotein receptor (Ldlr)-deficiency and a high-fat …
Altered brain expression and cerebrospinal fluid levels of TIMP4 in cerebral amyloid angiopathy
L Jäkel, AM De Kort, A Stellingwerf… - Acta Neuropathologica …, 2024 - Springer
Cerebral amyloid angiopathy (CAA) is a highly prevalent and progressive pathology,
involving amyloid-β (Aβ) deposition in the cerebral blood vessel walls. CAA is associated …
involving amyloid-β (Aβ) deposition in the cerebral blood vessel walls. CAA is associated …
Loss of TIMP3, but not TIMP4, exacerbates thoracic and abdominal aortic aneurysm
Aims Aorta exhibits regional heterogeneity (structural and functional), while different
etiologies for thoracic and abdominal aortic aneurysm (TAA, AAA) are recognized. Tissue …
etiologies for thoracic and abdominal aortic aneurysm (TAA, AAA) are recognized. Tissue …
[HTML][HTML] Targeted proteomics and metabolomics for biomarker discovery in abdominal aortic aneurysm and post-EVAR sac volume
Background and aims Abdominal aortic aneurysm (AAA) patients undergo uniform
surveillance programs both leading up to, and following surgery. Circulating biomarkers …
surveillance programs both leading up to, and following surgery. Circulating biomarkers …
Colorectal cancer chemotherapy drug bevacizumab may induce muscle atrophy through CDKN1A and TIMP4
Q Xu, J Li, Y Wu, W Zhou, Z Xu - Frontiers in Oncology, 2022 - frontiersin.org
The muscle in the organism has the function of regulating metabolism. Long-term muscle
inactivity or the occurrence of chronic inflammatory diseases are easy to induce muscle …
inactivity or the occurrence of chronic inflammatory diseases are easy to induce muscle …
MicroRNA-361-5p acts as a biomarker for carotid artery stenosis and promotes vascular smooth muscle cell proliferation and migration
F Wang, Y An, H Hao - BMC Medical Genomics, 2023 - Springer
Background Vascular smooth muscle cells (VSMCs) dysfunction participates in carotid artery
stenosis (CAS). The study aimed to examine the expression pattern of miR-361-5p in CAS …
stenosis (CAS). The study aimed to examine the expression pattern of miR-361-5p in CAS …