[HTML][HTML] Mesenchymal stem cell-derived secretome: a potential therapeutic option for autoimmune and immune-mediated inflammatory diseases

G Műzes, F Sipos - Cells, 2022 - mdpi.com
Immune-mediated inflammatory diseases (IMIDs) encompass several entities such as
“classic” autoimmune disorders or immune-mediated diseases with autoinflammatory …

[HTML][HTML] Therapeutic strategy of mesenchymal-stem-cell-derived extracellular vesicles as regenerative medicine

Y Matsuzaka, R Yashiro - International Journal of Molecular Sciences, 2022 - mdpi.com
Extracellular vesicles (EVs) are lipid bilayer membrane particles that play critical roles in
intracellular communication through EV-encapsulated informative content, including …

Cartilage regeneration and inflammation modulation in knee osteoarthritis following injection of allogeneic adipose-derived mesenchymal stromal cells: a phase II …

B Sadri, M Hassanzadeh, A Bagherifard… - Stem cell research & …, 2023 - Springer
Background Intra-articular injection of mesenchymal stromal cells (MSCs) with
immunomodulatory features and their paracrine secretion of regenerative factors proposed a …

The emerging role of regulatory cell-based therapy in autoimmune disease

F Ghobadinezhad, N Ebrahimi, F Mozaffari… - Frontiers in …, 2022 - frontiersin.org
Autoimmune disease, caused by unwanted immune responses to self-antigens, affects
millions of people each year and poses a great social and economic burden to individuals …

IL-33/ST2 axis in autoimmune disease

L Shakerian, H Kolahdooz, M Garousi, V Keyvani… - Cytokine, 2022 - Elsevier
Abstract Interleukin-33 (IL-33) is a member of the IL-1 family and plays an ambivalent role in
autoimmune diseases. IL-33 signals via the ST2 receptor and drives cytokine production in …

Knowledge map** of exosomes in autoimmune diseases: a bibliometric analysis (2002–2021)

F Wu, J Gao, J Kang, X Wang, Q Niu, J Liu… - Frontiers in …, 2022 - frontiersin.org
Background Autoimmune diseases (AIDs) are a class of chronic disabling diseases
characterized by inflammation and damage to muscles, joints, bones, and internal organs …

Research progress of engineered mesenchymal stem cells and their derived exosomes and their application in autoimmune/inflammatory diseases

X Zhu, D Ma, B Yang, Q An, J Zhao, X Gao… - Stem cell research & …, 2023 - Springer
Autoimmune/inflammatory diseases affect many people and are an important cause of
global incidence and mortality. Mesenchymal stem cells (MSCs) have low immunogenicity …

3D‐hUMSCs Exosomes Ameliorate Vitiligo by Simultaneously Potentiating Treg Cells‐Mediated Immunosuppression and Suppressing Oxidative Stress‐Induced …

Q Wang, W Guo, L Niu, Y Zhou, Z Wang… - Advanced …, 2024 - Wiley Online Library
Vitiligo is an autoimmune disease characterized by epidermal melanocyte destruction, with
abnormal autoimmune responses and excessive oxidative stress as two cardinal …

Exosomes derived from mesenchymal stem cells primed with disease-condition-serum improved therapeutic efficacy in a mouse rheumatoid arthritis model via …

EW Choi, IR Lim, JH Park, J Song, B Choi… - Stem Cell Research & …, 2023 - Springer
Backgrounds Rheumatoid arthritis (RA) is a chronic and systemic autoimmune disease
characterized by synovial inflammation-mediated progressive destruction of the cartilage …

Current cell therapies for systemic lupus erythematosus

LTM Dao, TT Vu, QT Nguyen, VT Hoang… - Stem Cells …, 2024 - academic.oup.com
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease in which multiple
organs are damaged by the immune system. Although standard treatment options such as …