Genomic surveillance for antimicrobial resistance—a One Health perspective
Antimicrobial resistance (AMR)—the ability of microorganisms to adapt and survive under
diverse chemical selection pressures—is influenced by complex interactions between …
diverse chemical selection pressures—is influenced by complex interactions between …
Genomics for public health and international surveillance of antimicrobial resistance
Historically, epidemiological investigation and surveillance for bacterial antimicrobial
resistance (AMR) has relied on low-resolution isolate-based phenotypic analyses …
resistance (AMR) has relied on low-resolution isolate-based phenotypic analyses …
Benchmarking reveals superiority of deep learning variant callers on bacterial nanopore sequence data
Variant calling is fundamental in bacterial genomics, underpinning the identification of
disease transmission clusters, the construction of phylogenetic trees, and antimicrobial …
disease transmission clusters, the construction of phylogenetic trees, and antimicrobial …
Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteria
Even in the setting of optimal resuscitation in high-income countries severe sepsis and
septic shock have a mortality of 20–40%, with antibiotic resistance dramatically increasing …
septic shock have a mortality of 20–40%, with antibiotic resistance dramatically increasing …
[HTML][HTML] Emergence of environmental antibiotic resistance: Mechanism, monitoring and management
The rapid development and spread of antimicrobial resistance in the post-antibiotic era has
become a global concern. Recent evidence indicates that, at present, antibiotic resistance is …
become a global concern. Recent evidence indicates that, at present, antibiotic resistance is …
Global emergence of a hypervirulent carbapenem-resistant Escherichia coli ST410 clone
Carbapenem-resistant Escherichia coli (CREC) ST410 has recently emerged as a major
global health problem. Here, we report a shift in CREC prevalence in Chinese hospitals …
global health problem. Here, we report a shift in CREC prevalence in Chinese hospitals …
The MAGMA pipeline for comprehensive genomic analyses of clinical Mycobacterium tuberculosis samples
TH Heupink, L Verboven, A Sharma… - PLoS Computational …, 2023 - journals.plos.org
Background Whole genome sequencing (WGS) holds great potential for the management
and control of tuberculosis. Accurate analysis of samples with low mycobacterial burden …
and control of tuberculosis. Accurate analysis of samples with low mycobacterial burden …
Artificial intelligence applications in the diagnosis and treatment of bacterial infections
X Zhang, D Zhang, X Zhang, X Zhang - Frontiers in Microbiology, 2024 - frontiersin.org
The diagnosis and treatment of bacterial infections in the medical and public health field in
the 21st century remain significantly challenging. Artificial Intelligence (AI) has emerged as a …
the 21st century remain significantly challenging. Artificial Intelligence (AI) has emerged as a …
“Smart markets”: harnessing the potential of new technologies for endemic and emerging infectious disease surveillance in traditional food markets
Emerging and endemic zoonotic diseases continue to threaten human and animal health,
our social fabric, and the global economy. Zoonoses frequently emerge from congregate …
our social fabric, and the global economy. Zoonoses frequently emerge from congregate …
Current uses and future perspectives of genomic technologies in clinical microbiology
I Bianconi, R Aschbacher, E Pagani - Antibiotics, 2023 - mdpi.com
Recent advancements in sequencing technology and data analytics have led to a
transformative era in pathogen detection and ty**. These developments not only expedite …
transformative era in pathogen detection and ty**. These developments not only expedite …