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Exosomes: large-scale production, isolation, drug loading efficiency, and biodistribution and uptake
I Kimiz-Gebologlu, SS Oncel - Journal of Controlled Release, 2022 - Elsevier
Exosomes are nanovesicles with different contents that play a role in various biological and
pathological processes. It offers significant advantages over other delivery systems such as …
pathological processes. It offers significant advantages over other delivery systems such as …
Exosome engineering in cell therapy and drug delivery
Cell-derived exosomes have opened new horizons in modern therapy for advanced drug
delivery and therapeutic applications, due to their key features such as low immunogenicity …
delivery and therapeutic applications, due to their key features such as low immunogenicity …
Noncoding RNA therapeutics—challenges and potential solutions
Therapeutic targeting of noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and
long noncoding RNAs (lncRNAs), represents an attractive approach for the treatment of …
long noncoding RNAs (lncRNAs), represents an attractive approach for the treatment of …
The application of mesenchymal stromal cells (MSCs) and their derivative exosome in skin wound healing: a comprehensive review
Recently, mesenchymal stromal cells (MSCs) and also their exosome has become a game-
changing tool in the context of tissue engineering and regenerative medicine. MSCs due to …
changing tool in the context of tissue engineering and regenerative medicine. MSCs due to …
A paradigm shift in cell-free approach: the emerging role of MSCs-derived exosomes in regenerative medicine
S Moghadasi, M Elveny, HS Rahman… - Journal of translational …, 2021 - Springer
Recently, mesenchymal stem/stromal cells (MSCs) due to their pro-angiogenic, anti-
apoptotic, and immunoregulatory competencies along with fewer ethical issues are …
apoptotic, and immunoregulatory competencies along with fewer ethical issues are …
Engineered extracellular vesicles for cancer therapy
X Zhang, H Zhang, J Gu, J Zhang, H Shi… - Advanced …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) have emerged as a novel cell‐free strategy for the treatment of
many diseases including cancer. As a result of their natural properties to mediate cell‐to‐cell …
many diseases including cancer. As a result of their natural properties to mediate cell‐to‐cell …
Prospects and challenges of extracellular vesicle-based drug delivery system: considering cell source
W Meng, C He, Y Hao, L Wang, L Li, G Zhu - Drug delivery, 2020 - Taylor & Francis
Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, are
nanosized membrane vesicles derived from most cell types. Carrying diverse biomolecules …
nanosized membrane vesicles derived from most cell types. Carrying diverse biomolecules …
Exosomes derived from pioglitazone-pretreated MSCs accelerate diabetic wound healing through enhancing angiogenesis
Y Hu, R Tao, L Chen, Y **ong, H Xue, L Hu… - Journal of …, 2021 - Springer
Background Enhanced angiogenesis can promote diabetic wound healing. Mesenchymal
stem cells (MSCs)-derived exosomes, which are cell-free therapeutics, are promising …
stem cells (MSCs)-derived exosomes, which are cell-free therapeutics, are promising …
Mesenchymal stromal cell secretome: influencing therapeutic potential by cellular pre-conditioning
JR Ferreira, GQ Teixeira, SG Santos… - Frontiers in …, 2018 - frontiersin.org
Mesenchymal stromal cells (MSCs) are self-renewing, culture-expandable adult stem cells
that have been isolated from a variety of tissues, and possess multipotent differentiation …
that have been isolated from a variety of tissues, and possess multipotent differentiation …
Mesenchymal stem cell-derived extracellular vesicles: challenges in clinical applications
Stem cell therapy has garnered much attention and application in the past decades for the
treatment of diseases and injuries. Mesenchymal stem cells (MSCs) are studied most …
treatment of diseases and injuries. Mesenchymal stem cells (MSCs) are studied most …