[HTML][HTML] Single-cell multiomics reveals persistence of HIV-1 in expanded cytotoxic T cell clones
Understanding the drivers and markers of clonally expanding HIV-1-infected CD4+ T cells is
essential for HIV-1 eradication. We used single-cell ECCITE-seq, which captures surface …
essential for HIV-1 eradication. We used single-cell ECCITE-seq, which captures surface …
Racial disparity in prostate cancer in the African American population with actionable ideas and novel immunotherapies
Abstract Background African Americans (AAs) in the United States are known to have a
higher incidence and mortality for Prostate Cancer (PCa). The drivers of this epidemiological …
higher incidence and mortality for Prostate Cancer (PCa). The drivers of this epidemiological …
Racial disparities in prostate cancer: A complex interplay between socioeconomic inequities and genomics
The largest US cancer health disparity exists in prostate cancer, with Black men having more
than a two-fold increased risk of dying from prostate cancer compared to all other races. This …
than a two-fold increased risk of dying from prostate cancer compared to all other races. This …
Comparative genomics reveals distinct immune-oncologic pathways in African American men with prostate cancer
Purpose: The role of immune-oncologic mechanisms of racial disparities in prostate cancer
remains understudied. Limited research exists to evaluate the molecular underpinnings of …
remains understudied. Limited research exists to evaluate the molecular underpinnings of …
More that ACE2? NRP1 may play a central role in the underlying pathophysiological mechanism of olfactory dysfunction in COVID-19 and its association with …
Three mechanisms have been proposed to account for COVID-19 associated olfactory
dysfunction; obstruction of the olfactory cleft; epithelial injury and infection of the …
dysfunction; obstruction of the olfactory cleft; epithelial injury and infection of the …
Challenges and Opportunities for Data Science in Women's Health
TL Edwards, CA Greene, JA Piekos… - Annual Review of …, 2023 - annualreviews.org
The intersection of women's health and data science is a field of research that has
historically trailed other fields, but more recently it has gained momentum. This growth is …
historically trailed other fields, but more recently it has gained momentum. This growth is …
Comparative transcriptomic, epigenomic and immunological analyses identify drivers of disparity in high-grade serous ovarian cancer
H Huang, R Keathley, U Kim, H Cardenas, P **e… - npj Genomic …, 2024 - nature.com
Black women face the highest mortality-to-incidence ratio from high grade serous ovarian
cancer (HGSOC). This study investigated biological differences in HGSOC tumors from …
cancer (HGSOC). This study investigated biological differences in HGSOC tumors from …
The relationship between lipoprotein A and other lipids with prostate cancer risk: A multivariable Mendelian randomisation study
Background Numerous epidemiological studies have investigated the role of blood lipids in
prostate cancer (PCa) risk, though findings remain inconclusive to date. The ongoing …
prostate cancer (PCa) risk, though findings remain inconclusive to date. The ongoing …
Analysis of circulating immune biomarkers by race in men with metastatic castration-resistant prostate cancer treated with sipuleucel-T
JE Hawley, S Pan, H Kandadi… - JNCI: Journal of the …, 2022 - academic.oup.com
Among racial subgroups, Black men have the highest prostate cancer–specific death rate,
yet they also exhibit prolonged overall survival compared with White men when treated with …
yet they also exhibit prolonged overall survival compared with White men when treated with …
Minority children experience a higher risk of death from many central nervous system tumor types even after accounting for treatment received: A National Cancer …
KJ Moore, CL Moertel, LA Williams - Cancer, 2022 - Wiley Online Library
Background Brain tumors are the leading cause of death from disease in children.
Racial/ethnic minority children have poorer outcomes than White children; however, it is not …
Racial/ethnic minority children have poorer outcomes than White children; however, it is not …