Preclinical and clinical effects of Nigella sativa and its constituent, thymoquinone: A review

Z Gholamnezhad, S Havakhah… - Journal of …, 2016 - Elsevier
Ethnopharmacological relevance Nigella sativa (N. sativa) L.(Ranunculaceae), well known
as black cumin, has been used as a herbal medicine that has a rich historical background. It …

Plant essential oils as healthy functional ingredients of nutraceuticals and diet supplements: A review

R Matera, E Lucchi, L Valgimigli - Molecules, 2023 - mdpi.com
Essential oils (EOs) are mixtures of volatile molecules endowed with health-promoting
biological activities that go beyond their role as aromas and natural preservatives and can …

Nigella plants–Traditional uses, bioactive phytoconstituents, preclinical and clinical studies

B Salehi, C Quispe, M Imran, I Ul-Haq… - Frontiers in …, 2021 - frontiersin.org
Nigella is a small genus of the family Ranunculaceae, which includes some popular species
due to their culinary and medicinal properties, especially in Eastern Europe, Middle East …

Mineral oil: safety and use as placebo in REDUCE-IT and other clinical studies

B Olshansky, MK Chung, MJ Budoff… - European Heart …, 2020 - academic.oup.com
Mineral oil is often used as a clinical trial placebo. Pharmaceutical-grade mineral oil consists
of a mixture of saturated hydrocarbons, with a purity and chemical structure that differs …

Effects of Nigella Sativa on Type-2 Diabetes Mellitus: A Systematic Review

A Hamdan, R Haji Idrus, MH Mokhtar - International journal of …, 2019 - mdpi.com
Diabetes mellitus is one of the most prevalent metabolic disorders that affect people of all
genders, ages, and races. Medicinal herbs have gained wide attention from researchers and …

Nigella sativa in controlling Type 2 diabetes, cardiovascular, and rheumatoid arthritis diseases: Molecular aspects

V Hadi, N Pahlavani, M Malekahmadi… - Journal of Research …, 2021 - journals.lww.com
Oxidative stress is an important factor in the etiology of several chronic diseases that include
cardiovascular disease (CVD), Type 2 diabetes (T2D), and rheumatoid arthritis (RA) …

Nigella sativa L. and Its Active Compound Thymoquinone in the Clinical Management of Diabetes: A Systematic Review

MF Mahomoodally, MZ Aumeeruddy… - International journal of …, 2022 - mdpi.com
Despite existing conventional hypoglycemic drugs to manage diabetes, their non-availability
and cost in low-income countries coupled with the associated side effects remain a major …

Nigella sativa improves glucose homeostasis and serum lipids in type 2 diabetes: A systematic review and meta-analysis

R Daryabeygi-Khotbehsara, M Golzarand… - … therapies in medicine, 2017 - Elsevier
Background & objective (s) Global prevalence of type 2 diabetes (T2D) is very high and is
currently growing alarmingly. With respect to recent researchers' attention to the potential …

Effectiveness and safety of Ayurvedic medicines in type 2 diabetes mellitus management: a systematic review and meta-analysis

K Chattopadhyay, H Wang, J Kaur, G Nalbant… - Frontiers in …, 2022 - frontiersin.org
Introduction: Many Ayurvedic medicines have the potential for managing type 2 diabetes
mellitus (T2DM), with previous systematic reviews demonstrating effectiveness and safety for …

The effects of Nigella sativa L. on obesity: A systematic review and meta-analysis

N Namazi, B Larijani, MH Ayati, M Abdollahi - Journal of …, 2018 - Elsevier
Ethnopharmacological relevance Nigella sativa L.(N. sativa) is a traditional herbal medicine
that has been used for centuries to treat rheumatoid arthritis, diabetes, asthma, and other …