2-Pyrone natural products and mimetics: isolation, characterisation and biological activity

GP McGlacken, IJS Fairlamb - Natural product reports, 2005 - pubs.rsc.org
Covering: December 1992 to December 2004 The review summarises natural products
containing the 2-pyrone moiety. An emphasis has been placed upon the biological activity …

Natural and synthetic 2H-pyran-2-ones and their versatility in organic synthesis

A Goel, VJ Ram - Tetrahedron, 2009 - Elsevier
The pyran ring system is widely present in the animal and plant kingdom and possesses
diverse pharmacological activities. Pyran is a six-membered oxygen heterocycle with two …

Biosynthesis, total syntheses, and antitumor activity of tanshinones and their analogs as potential therapeutic agents

Y Dong, SL Morris-Natschke, KH Lee - Natural product reports, 2011 - pubs.rsc.org
Covering: 1968 to June 2010 Tanshinones are a series of abietane diterpenes, isolated
exclusively from Salvia miltiorrhiza and related species. More than 40 tanshinones and their …

Recent advances in the chemistry of 1, 3-diketones: Structural modifications and synthetic applications

AV Kel'in, A Maioli - Current Organic Chemistry, 2003 - benthamdirect.com
Major aspects of the synthetic utility of 1, 3-diketones are reviewed with special emphasis
being placed on the regioselectivity of the transformations. The unsymmetrical 1, 3-diketone …

A Formal [3+ 3] Cycloaddition Approach to Natural‐Product Synthesis

RP Hsung, AV Kurdyumov… - European journal of …, 2005 - Wiley Online Library
Abstract A formal [3+ 3] cycloaddition strategy for constructing complex heterocycles is
reviewed here. This formal cycloaddition involves condensation of α, β‐unsaturated iminium …

Complex α–Pyrones Synthesized by a Gold-Catalyzed Coupling Reaction

T Luo, SL Schreiber - Angewandte Chemie (International ed …, 2007 - pmc.ncbi.nlm.nih.gov
We have been exploring a strategy for the synthesis of small molecules having properties
that increase the probability of success in all facets of probe-and drug-discovery pipelines …

Recent advances in the synthesis of 1, 3-diketones

AV Kel'in - Current Organic Chemistry, 2003 - benthamdirect.com
The most recent achievements in the construction of the 1, 3-diketone moiety are reviewed.
Though both classical and modern approaches to the synthesis of 1, 3-diketones are …

2H-Pyran-2-ones and their annelated analogs as multifaceted building blocks for the fabrication of diverse heterocycles

R Pratap, VJ Ram - Tetrahedron, 2017 - Elsevier
Abstract 2H-Pyran-2-ones are widely present in nature and found as either isolated or in
fused form. Depending on the fusion of benzene ring, pyran can give coumarins …

Stereoselective Formal [3 + 3] Cycloaddition Approach to cis-1-Azadecalins and Synthesis of (−)-4a,8a-diepi-Pumiliotoxin C. Evidence for the First Highly …

HM Sklenicka, RP Hsung, MJ McLaughlin… - Journal of the …, 2002 - ACS Publications
Evidence is described here to support that a highly stereoselective 6π-electron electrocyclic
ring closure of 1-azatrienes is a key step in formal [3+ 3] cycloaddition or annulation …

[HTML][HTML] Enzymatic one-step synthesis of natural 2-pyrones and new-to-nature derivatives from coenzyme A esters

S Manoilenko, M Dippe, T Fuchs… - Journal of …, 2024 - Elsevier
The 2-pyrone moiety is present in a wide range of structurally diverse natural products with
various biological activities. The plant biosynthetic routes towards these compounds mainly …