For more than one century, brain processing was mainly thought in a localizationist
framework, in which one given function was underpinned by a discrete, isolated cortical …

Collecting comprehensive data sets of the same subject has become a standard in
neuroscience research and uncovering multivariate relationships among collected data sets …

Studies of humans with focal brain damage and non-human animals with experimentally
induced brain lesions have provided pivotal insights into the neural basis of behavior. As the …

Stroke causes focal brain lesions that disrupt functional connectivity (FC), a measure of
activity synchronization, throughout distributed brain networks. It is often assumed that FC …

Clinicians and scientists alike have long sought to predict the course and severity of chronic
post-stroke cognitive and motor outcomes, as the ability to do so would inform treatment and …

Neuroscience has a long history of inferring brain function by examining the relationship
between brain injury and subsequent behavioral impairments. The primary advantage of this …

Lesion studies are an important tool for cognitive neuroscientists and neurologists. However,
while brain lesion studies have traditionally aimed to localize neurological symptoms to …

Cognitive control modulates other cognitive functions to achieve internal goals and is
important for adaptive behavior. Cognitive control is enabled by the neural computations …

Understanding neural circuits that support mood is a central goal of affective neuroscience,
and improved understanding of the anatomy could inform more targeted interventions in …

The functional roles of the precuneus are unclear. Focal precuneus lesions are rare, making
it difficult to identify robust brain–behavior relationships. Distinct functional subdivisions of …